Many of you are still questioning my use of tE2 gel? The gel and the E2 Patch are basically an old therapy which was taken off the market in 1985 due to an increase in cardiovascular issues and replaced with the extremely profitable and 'QOL reducing' jabs called Lupron or Zolodex. Prior to that time most men who experienced Biochemical Recurrence (BCR) of prostate cancer after primary treatments were given an inexpensive, synthetic, and very effective estrogen pill called Diethylstilbestrol (DES). This pill did a great job of keeping PCa sleeping for many men with advanced PCa; however, because it was an oral hormone it was absorbed in the liver and 'could' cause CV problems. The pharmaceutical companies blamed the pill even if the men were predisposed to CV problems from other causes; consequently, banning its use and came up with jabs costing an average of $2,000/month.
Since the gel is absorbed directly into the blood through the skin it bypasses the 'first pass hepatic metabolism' thus avoiding the coagulants created in the liver.
As I mentioned numerous times before, grandpa, my father, and his two brothers all were treated with DES and never had any side effects or CV issues until 1985 when they were switched to Lupron...they didn't have CV problems; however, the side effects were significant.
I had read that one of our brainy gurus, pjoshea13 found a source for DES.
Transdermal Estrogen + ADT {was Zometa}
