Situation: Age 75 Based in UK (Scotland): 2018. Gleason score 3+4 - 7. Biopsy was 12 core with 8 targeted. Results were targeted 8 = 4 positive - General 4 = Nil positive. Noted as Stage T3a. PSA 33.2 but no mets and MRI/Bone Scan and x-ray all show no indication that PC has spread other than bulging of the capsule.
Started formal treatment in Dec 18 – was advised that cancer was Locally Advanced - Treatment started with 3 weeks of Bicalutamide then overlapped with Lupron with a one-month injection late December 18, followed by a program of 3-month injections Jan 19 through to Oct 20. Treatment included 22 sessions VMAT (RapidArc) which was completed in Jul 19, resulting in 60 Grey over a four-week period.
During Lupron treatment, PSA level of <0.1 was recorded on all bloods post Apr 19 to until Oct20, and T showing <1.0.
Completed Lupron treatment (7 x 3monthly injections) Jul 20.
Entered Active Surveillance with blood tests every 3 months until Jul 21.
Blood tests reduced to every 6 months after Jul 21, last one being Mar 23.
Figures as follows: Jul 21 - T15.7 PSA 0.1; Oct 21 T14.6 PSA 0.1; Feb 22 T18.3 PSA 0.1; Oct 22 T16.3 PSA 0.1; Mar 23 T22.1 PSA 0.1
Currently my T is rising and my PSA remains static.
I have consultation with my consultant Oncologist 14th April, so what would I expect his recommendations to be regarding continued treatment?
Any thoughts/comments appreciated.
Thanks
Written by
StuartS
To view profiles and participate in discussions please or .
Hi chaddfgc., currently no side effects however, I completed the Lupron injections in Jul 20, but had numerous side effects through until Aug 21. Brain fog, depression..., short tempered etc., so was relieved to eventually complete the Lupron and get my life back to something like normal.
This is the first time in my SBRT/ADT post radiaton that I've heard of the term " Brain Fog" which explains my golf game frustrations. Seriously now I know it's not my fault. Thanks for that.
I had my last Lupron shot June 2022. Side affects were hot flashes, lack of energy etc. That is all in the past. My testosterone is just now starting to recover. PSA a month ago was .05 up from .03. Testosterone was only 31, I was hoping for a quicker recovery.
Hopefully, salvage radiation of the entire pelvic lymph node area + 2 years of hormone therapy can still provide a cure. I wouldn't wait for a PET scan.
Yes, I was responding to your post. My purpose wasn't to criticize your doctors, it was to help you understand why your treatment may have failed, and how you can still correct it.
TA..., many thanks for the clarification. I will fully digest the reports. However, I did have 2 years ADT the 7th three monthly Lupron injection was at month 21, and would have been in my system at the two year point..., or so I was advised by my cancer team. I am somewhat concerned however by your comment that my treatment may have failed! What have I missed? I understood (again from my cancer support team), that I was doing good. PSA stable and T just above the preferred max 20.
What should my Onc consultant be advising regarding additional treatment on Friday?
Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.
Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.
Update after 6 months on SARMS Osterine and Carderine along with ADT
looking for next steps for my young husband
BCR but Neg PSMA scan, ? appropriate next step
Still on ADT and look what it has done :-)
Lupron and xygeva only
