PSA going up after docetaxel and zytiga - Advanced Prostate...

Advanced Prostate Cancer

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PSA going up after docetaxel and zytiga

longleaf profile image
7 Replies

Mike was diagnosed with stage 4 prostate cancer in April 2019. He did a month of firmagon and has been on lupron since. In June 2019 he started 6 treatments of docetaxel and his psa went down but two months later it was rising again. He was entered in a trial where Zytiga was added to his treatments (and the trial treatment was olaparib, but based on how his bloodwork is we think he is in the control arm-but I guess we can't say that definitively). His genetic tests did not indicate any of the markers that respond to olaparib; but it was a trial. His psa went down to .03 on the zytiga. It was .04 last month and now is .05. The Dr. says that he will probably need to shift treatments in 5 or 6 months and mentioned the possibility of psma treatment. Mike is being treated at Tulane University.

While on this treatment his scans indicated that the cancer shrank in the lymph nodes and bones so that they were not really detectable. I think next month he will get scans again.

I am interested in possible options if the cancer is starting to progress.

Thank you for whatever you want to share.

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longleaf
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7 Replies
Tall_Allen profile image
Tall_Allen

Great response! Is Sartor his MO?

longleaf profile image
longleaf in reply to Tall_Allen

He started with Sartor but they moved him to Dr Barrata after a while.

Tall_Allen profile image
Tall_Allen in reply to longleaf

Ask about the Th-227 trial there after Zytiga.

Geolo85 profile image
Geolo85

My husband has a first visit with Dr. Sartor late August for consult after five failed treatments in just over three years. Are you happy with Dr. Barata and do you think Dr. Sartor is still involved with your husband's treatment plan? Sending good thoughts that your husband gets alot more than just a few more months on Zytiga.

longleaf profile image
longleaf in reply to Geolo85

My husband has been happy with dr. Barrata. I am not sure how involved Dr Sartor is anymore, but I think we can ask for him back if we wanted.

longleaf profile image
longleaf in reply to Geolo85

Thank you. Good thought sadie you and your husband as well.

longleaf profile image
longleaf in reply to longleaf

To you (not sadie). Darn autocorrect

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