Dad - 36 Months from dx, still not castrate resistant

[Jlcwonderboy]

Some time ago I posted my father's regular test scores for a full year from diagnosis, some found them useful, so I thought I would provide them again, and this time with an update of his most recent results. We are in the UK and he was diagnosed in July/Aug 2017, had 6 rounds of docetaxel in the Autumn of 2017 and has been on the STAMPEDE PATCH trial for a couple of years (where he applies transdermal oestradiol patches rather than ADT injections).

Not sure for how much longer he will hold off being castrate resistant, but the continued low PSA and Testosterone suggests he might be hanging round for a little while longer (fingers crossed!)

Aug-17 PSA: 29 ALP: 160

Aug-17 PSA: 2.7 ALP: 136

Sep-17 PSA: 1.2 ALP: 75 TES: <0.4 E2: 676

Oct-17 PSA: 0.4 ALP: 62

Oct-17 PSA: 0.2 ALP: 66 TES: <0.4 E2: 239

Nov-17 PSA: 0.2 ALP: 72 TES: <0.4 E2: 311

Dec-17 PSA: 0.2 ALP: 62 TES: <0.4 E2: 237

Feb-18 PSA: 0.2 ALP:59 TES: <0.4 E2: 566

May-18 PSA: 0.1 ALP: 52 TES: <0.4 E2: 614

Jul-18 PSA: <0.03 ALP: 44 TES: <0.4 E2: 403

...

Nov-19 PSA: <0.03 ALP: 53 TES: <0.4 E2: 943

Feb-20 PSA: <0.03 ALP: 45 TES: <0.4 E2: 1413

Aug-20 PSA: <0.03 ALP: 38 TES: <0.4 E2: 1217

[Magnus1964]

Great numbers, I take it that he has not had other ADT drugs. So he probably going to be around for a long time.

[Jlcwonderboy in reply to Magnus1964]

Yes, apart from some Lupron early on, the patches since and 6 rounds of docetaxel he’s had nothing else. So hopefully things up our sleeve as and when we need them

[SPEEDYX]

Looks like 3 years and will be counting for many more years!!!

[Tall_Allen]

Encouraging! Any side effects of treatment?

[Jlcwonderboy in reply to Tall_Allen]

Some gynaecomastia and general tiredness, but no hot flushes or anything like that

[j-o-h-n]

Jolly good show.........

Good Luck, Good Health and Good Humor.

j-o-h-n Thursday 09/03/2020 7:49 PM DST

[JNunes]

I'm glad for you. It is very encouraging.