Renal neoplasm

[Cynthgob]

Husband has extensive bone mets and has had chemo and zytiga. 3 years since diagnosed . Now scans show renal neoplasm on left kidney. What is the standard of care on this? We realize he has a very bad cancer and don’t want to put him thru extraordinary measures . He wants to enjoy life now.

[Cynthgob]

Psa gradually going up has been on zytiga 18 months. 8.5 psa

[Tall_Allen]

Has he had Jevtana? He can get by with one functioning kidney.

[Cynthgob in reply to Tall_Allen]

No jetvana. Is that is hard on you as docetaxel ? He doesn’t want any more chemo . He said he lost six months of his life and it doesn’t seem like it extends life very much longer. At most he will most likely get 2 years but he wants to remain active and then go quickly.

[Hidden in reply to Cynthgob]

I’m sorry that he is suffering so . Tuff decisions , None really clear cut . We all want to remain active then go quickly . QOL is important. This treatment game we play is roulette .

[Cynthgob in reply to Hidden]

QOL is the main thing for him

[Hidden in reply to Cynthgob]

As it should be. Peace to you both in the storm.🙏

[Magnus1964]

He might try Provenge.

[Cynthgob]

We did meet with a geneticist at hospital and they did blood tests. Found no mutations. They have now mentioned a bone biopsy to find mutations.

[tango65]

If his cancer is PSMA positive (it could be determined by biopsy, or PSMA PET/CT, Ga 68 or DCFPyl), he could consider treatment wit Lu 177 PSMA and or Ac 225 which could help to control the cancer for a while with much less negative side effect than chemo. He could, if possible financially go to Germany or Australia or consider some of the clinical trials in the USA,

clinicaltrials.gov/ct2/resu...

Biopsy and genetic studies could be also useful to determine if the cancer could be treated with specific drugs, such as Keytruda, Olaparib, Rucaparib etc.

[Rkoma]

Some people try Pfeifer protocol.

You can read more about it here

pfeifer-protocol.com/integr...

Regards

Rkoma