I have been on Lupron since November, 2018. I have probably had all of the frequently mentioned side effects and they have significantly decreased the quality of my life. Four weeks ago, generic Zytiga was added because my PSA was increasing and a PET-CT scan showed mets in lymph nodes in my upper body. It seems like the side effects are much worse. I have noticed that for the past week or so, I have been having wild mood changes, mostly in a bad direction.
While it seems entirely possible that my mod swings are because I have reached the tipping point with everything that has been going on in the USA, I wonder if anyone else has found mood changes that seem to be associated with starting Zytiga.
I haven't seen this listed as a side effect of Zytiga anywhere and will discuss it with my MO, but would like to hear from the community.
Don
Diagnosed by biopsy in October, 2018. Ten of 12 samples were positive, GS of 7 or 8 in 9 of those.
CT-MET at that time should likely involvement with the lymph nodes local to the prostate
Peak PSA was 18.
Treatment is at Shands (UF in Gainesville, FL), both RO and MO.
Thirty nine radiation treatments starting in December, 2018.
PSA ndair was 0.07.
Before starting Zytiga, PSA jumped from 0.14 to 0.58 in 3 months.
Will have PSA and CMP (to look at liver enzymes) next week.