Vitamin C combined With Green Tea - Advanced Prostate...

Advanced Prostate Cancer

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Vitamin C combined With Green Tea

Currumpaw profile image
13 Replies

This is old but relevant. I came across this while looking up something that pjoshea13 had posted last year about ibuprofen and green tea.

The link to vitamin C and green tea:

news.uns.purdue.edu/x/2007b...

The post pjoshea13 once made about ibuprofen and green tea -- not the NCBI version he posted but the same study:

researchgate.net/publicatio......

Uhhh--Why do any of us have cancer? These things probably stabilize or slow cancer.

Medicinal Traditionals Green Tea with Ginger with a little ginger powder or Nature's Best Ginger Extract added to it. When the fluoroquinolones ate up the repaired ligament in my back I drank four cups of this tea loaded with both types of ginger while taking ibuprofen and the two 81 mg aspirin I take in the AM. In a couple hours I was able to move okay. That ligament had healed in 1988.

Currumpaw

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Tall_Allen profile image
Tall_Allen

• High doses of oral Vitamin C can quench the ROS one needs to destroy the cancer. IV Vitamin C may have a beneficial pro-oxidant effect, but clinical trials are not yet mature.

• Green tea catechins may also have this effect and should be particularly avoided with radiation (including radiopharmaceuticals):

ncbi.nlm.nih.gov/pubmed/216...

• Green tea has been proven to have no benefit for prostate cancer:

ncbi.nlm.nih.gov/pmc/articl...

pagepressjournals.org/index...

• COX-2 inhibition with Celebrex has been proven to have no benefit in prostate cancer. The exception seems to be when it is combined with Zometa.

meetinglibrary.asco.org/rec...

Currumpaw profile image
Currumpaw in reply toTall_Allen

Hey T_A!

Thanks!

Just some of many articles on the net.

sciencedaily.com/releases/2...

High-dose vitamin C: Can it kill cancer cells? - Mayo Clinic

mayoclinic.org/diseases-con...

It is worth mentioning again that the Japanese have been prescribing PSK, Polysaccharide K for patients receiving chemo with success. PSK is Turkey Tail mushroom. It strengthens the immune system.

There is synergy in life. Synergy in treatment may hold answers.

As always, one should keep their health care providers advised as to what conventional and alternative treatments they wish to or are receiving.

Currumpaw

Graham49 profile image
Graham49 in reply toTall_Allen

The trial you post is for prevention, it does not "prove" green tea has no effect for existing prostate cancer.

Tall_Allen profile image
Tall_Allen in reply toGraham49

True. But it does make it very unlikely.

Currumpaw profile image
Currumpaw in reply toTall_Allen

Hey T_A!

Below the original study pjoshea13 referred to. I had saved it in it's entirety for quick reference.

ncbi.nlm.nih.gov/pubmed/182...

Anticancer Res. 2007 Nov-Dec;27(6B):3947-56.

Synergistic cell death by EGCG and ibuprofen in DU-145 prostate cancer cell line.

Kim MH1, Chung J.

Author information

1

Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, Texas 76107, USA. mkim@hsc.unt.edu

Abstract

BACKGROUND:

One of the green tea components epigallocatechin-3-gallate (EGCG) significantly prevented the growth of prostate cancer cells. In this study, synergistic effect of EGCG and ibuprofen (EGCG+ibuprofen) was investigated to determine their anti-proliferative and pro-apoptotic action in DU-145 prostate cancer cells.

MATERIALS AND METHODS:

Cell death analysis, immunoblotting, RT-PCR analysis, and caspase activity assay were used.

RESULTS:

EGCG+ibuprofen treatment resulted in 90% growth inhibition, while ibuprofen or EGCG alone reduced cell numbers by 25% and 20%, respectively. EGCG+ibuprofen induced MAPK activation, caspase activation and the inhibition of Bfl-1 expression, all of which were blocked by the antioxidant, N-acetyl-L-cysteine (NAC). Moreover, addition of ceramide rescued the NAC-inhibited MAPK activation and pretreatment with the ceramide synthase inhibitor, fumonisin B1, reduced cell death.

CONCLUSION:

Our results suggest that in DU-145 prostate cancer cells: (i) EGCG+ibuprofen treatment has a synergistic effect on apoptosis, and (ii) oxidative stress, directly or indirectly via ceramide synthesis mediates pro-apoptotic signaling.

PMID:

18225555

[Indexed for MEDLINE]

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Currumpaw

Tall_Allen profile image
Tall_Allen in reply toCurrumpaw

Hey Currumpaw- What you posted is just a lab test, and like all lab tests, should be ignored after there is contrary clinical evidence. This happens over 90% of the time.

Currumpaw profile image
Currumpaw in reply toTall_Allen

Hey T_A!!

Thanks for getting back!

Do you now of any clinical tests that combine ibuprofen and green tea as the study that pjoshea13 posted? If not, why hasn't such a study been done?

The study by the non profit that in Dr. Greger's YouTube video led to another study resulting in the supplement Pomi-T being formulated--as well as some noted urologists offering their own versions sold through their practice. Some of the men on HU supplement with Pomi-T.

"Pomi-T ® is clinically proven to have a significant benefit in real people in real life situations in a study designed by a team of experts led by The British Oncology Association “Doctor of the Year”. Pomi-T ® is made under the strictest quality assurance standards with testing for purity and authenticity.

HealthScoop | Pomi-T® 60 Capsules

myhealthscoop.com/shop/holi...

Currumpaw

Tall_Allen profile image
Tall_Allen in reply toCurrumpaw

It hasn't been pursued because green tea and celecoxib have shown no evidence of efficacy. The only ingredient in Pomi-T that has shown efficacy is sulforaphane.

Currumpaw profile image
Currumpaw in reply toTall_Allen

Hey T_A!

Interesting video about a study funded by a non profit, leading to another study that resulted in the formulation of Pomi-T .

youtu.be/E-uE3MVS8H0

Synergy! I think you'll enjoy the video but still have reservations and valid rebuttals. Dr. Greger had an older video on YouTube about this study that had more info. I believe that those conducting the study tried the four supplements one at a time, drew blood after digestion and drizzled the blood on the cultivated prostate cancer cells. No supplement alone came close to the effectiveness of all four combined. They stopped at the four--because the funding from the non profit ran out. I wonder what they would have added as the fifth ingredient had the funding still existed? Hmmmm?

I don't use the supplement Pomi-T. Although Pomi-T receives excellent reviews it is a proprietary blend. I prefer to do my own mix. Pomi-T is convenient and according to the studies effective. One pill--one and done!

Currumpaw

Tall_Allen profile image
Tall_Allen in reply toCurrumpaw

I don't get my info from Youtube videos.

Currumpaw profile image
Currumpaw in reply toTall_Allen

Hey T_A!

He is reviewing a clinical study, funded by a non profit that led to another clinical study which led to the formulation of Pomi-T!

If interested access these clinical studies and please critique them. I'm sure that the men taking Pomi-T would have an interest in negative info about Pomi-T as they have certainly been influenced to use this supplement by the positive studies.

Your critique and opinion have weight. Mine doesn't. Maybe Pomi-T is based on several flawed studies?

Currumpaw

Tall_Allen profile image
Tall_Allen in reply toCurrumpaw

I've read the published study of Pomi-T. The only ingredient in it that might have an effect is sulforaphane. All the others have been ruled out.

j-o-h-n profile image
j-o-h-n in reply toCurrumpaw

To me Green Tea tastes like I'm getting an internal tattoo.....(and it's my ex-wife's name)...

Good Luck, Good Health and Good Humor.

j-o-h-n Tuesday 03/24/2020 5:36 PM DST

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