New member, need help

[nadhhere]

Diagnosed metastatic prostate adenocarcinoma with neuroendocrine differentiation in June 2019. Only symptom was urinary retention. Stage IV, Gleason score 10. Poorly differentiated carcinoma. 66 yr old. When diagnosed, PSA was 21.

Undergoing ADT hormone therapy once in 3 months...Completed 6 cycles of chemotherapy (docetaxel) with 21 days gap between each cycle. Current PSA is 1.9

Now can't walk properly... feeling that legs r weak...due to pain difficult to sit...Dr suggested spine MRI, waiting for the MRI report.

Anybody having similar issues ?

[LearnAll]

Your PSA response is very good. A solid 91% down from the initial reading. Thats of course a positive news

Now, the pain...Is it bone pain ? If yes it comes from damage to bones by cancer cells. A simple way of knowing status of bones is by checking Alkaline Phosphatage leve. What is your Alk Phosphatase (ALP) level ?

Further treatment depends on MRI findings....might require Radiation to affected parts.

[nadhhere in reply to LearnAll]

ALP level is not tested. MRI is scheduled on January 1st

[LearnAll in reply to nadhhere]

ALP is a good indicator of overall status of bone metastasis. Its inexpensive test. I dont know why they did not test it. Anyway, lets see what MRI shows tomorrow ?

[nadhhere in reply to LearnAll]

Yes... waiting for MRI

[Tall_Allen]

Here are some clinical trials you may wish to discuss with your oncologist:

pcnrv.blogspot.com/2016/12/...

[Tall_Allen in reply to Tall_Allen]

You may also wish to consult with Misha Beltran at Dana Farber - this is what she specializes in.

[nadhhere in reply to Tall_Allen]

Thanks my friend...