Clioquinol (Zinc Ionophore) and Cabergoline (Prolactin Dopamine Agonist) for the Treatment of Terminal Androgen-independent Prostate Cancer?

ncbi.nlm.nih.gov/pmc/articl...

The role of prolactin in CRPC.

Clioquinol could be taken as a cream!

Conclusions

Terminal androgen-independent prostate is prolactin dependent, decreased zinc, ZIP1- deficient malignancy in which conditions that will increase zinc uptake and accumulation will exhibit cytotoxic/tumor suppressor effects.

Experimental studies demonstrate that the topical cutaneous application of 3% clioquinol cream will provide transdermal absorption of clioquinol into blood, which will result in mobile ZnCQ that is delivered to malignant sites, transports zinc into the ZIP-deficient malignant cells, and induces cytotoxic/tumor suppression effects. Treatment with the dopamine agonist, cabergoline, will decrease plasma prolactin level, thereby preventing prolactin-induced progression of androgen-independent malignancy.

FDA “Compassionate use” policies should permit clioquinol and cabergoline treatment of terminal androgen-independent cancer and without unnecessary delay.

And here a very interesting case: ncbi.nlm.nih.gov/pmc/articl...

[NPfisherman]

Thanks for posting...for the files....

Don Pescado

[Hidden in reply to NPfisherman]

ncbi.nlm.nih.gov/pmc/articl...

Another option!

[NPfisherman in reply to Hidden]

At this point, I take zinc citrate caps 50 mg qd as does pjoshea13---I can do those without needing an MD to RX.... Thanks again....

Don Pescado

[Hidden in reply to NPfisherman]

my husband too, but we are not sure that it reaches the prostate (as Patrick also mentioned to me). But another zinc ionophore is quercetin, as well as ECGC, so taking together might be a good idea.

[Ralph1966 in reply to Hidden]

You mean taking quercetin and ECGC (green tea) together?

[Hidden in reply to Ralph1966]

Quercetin or ECGC together with zinc citrate.

[PhilipSZacarias in reply to Hidden]

Hats off to you. Your husband is most fortunate to have you undertaking the research. Thank you for posting! Cheers, Phil

[j-o-h-n]

So I said to my wife "Dear wifey what do you think about Clioquinol (Zinc Ionophore) and Cabergoline (Prolactin Dopamine Agonist) for the Treatment of Terminal Androgen-independent Prostate Cancer?" Her answer from the kitchen was "are you high again?"

Good Luck, Good Health and Good Humor.

j-o-h-n Saturday 07/20/2019 7:02 PM DST

[Spyder54]

This article was discussed previously. One of the guys on our forum is Patient XY! Only his results were not long lasting. If you search for Cabergoline, you will see the discussion. Personally, I was let down because it seems like an Ahhhh-Ha moment.

Great post as we all present differently and react to therapies differently.. what works for you, may not work for me. What is crazy is that despite all the research, and progress, death rates still climbing with PCa and Breast Cancer.