On Zytiga but PSA still Climbing

[ewhite999]

I’m on Zytiga for 6 months now but my PSA has risen from 0.3 to 1 in the past 3 months. I already did chemo and Provenge two years ago. Also been taking Lupron and Xgeva for past two years. No bone pain, three small mets. I think I’ve received all available treatment short of radiation and/or removal which my docs are not recommending. Anyone know of other options?

[cesanon]

Lu177 treatment?

[ewhite999 in reply to cesanon]

First I’ve heard of it. I’ll check it out. Thanks

[cesanon in reply to ewhite999]

There is a lot on it in this forum.

You basically need to go to Germany or Australia to get it.

[Tall_Allen]

Try switching from prednisone to dexamethasone with your Zytiga. If chemo worked once, it may still work, or you can switch from Taxotere to Jevtana. And then re-challenge with Zytiga. Xofigo. Lots of clinical trials.

[tallguy2]

I would get a second opinion or irradiating the 3 "small mets" if they haven't already received the lifetime does.