please tell me the psa results once you started this combo and the drop in psa over time, does it take months before psa drops or does or should it happen quickly?
mine was at 55.2 down to 38.3 then 39.4 in past two months so sm now wondering as tal thought, I am too late to start this combo?
I do not want to waste yet more time if zytiga is not going to work as I already lost 8 months to get started in this drug change!
Thanks boys!!!
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billyboy3
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At biochemical recurrence following RP (Gleason 9, Stage 3b), after one year, my husband became detectable in with doubling at low levels of only one month. At a PSA of .273, a few subcentimeter retrocaval (lower back abdominal area) nodes were moderately avid on PSMA Pet Scan. He was immediately started on Casodex/Lupron. Then two weeks later, dropped Casodex and began Abiraterone/Prednisone combined with Lupron. After only one month, he dropped from 0.273 to <0.001. It worked fast. He was a super responder. We radiated the nodes, as well as salvage IMRT to the pelvis and pray we bought him lots of time. The avid nodes melted away at the end of the IMRT. He had an immediate response to the ADT, but it is my understanding that it can take a bit longer if a patient still has an intact prostate.
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