Very Young Guy, Kitchen Sink Guinea Pig

[AlooGobi]

Hi all - I’m reposting a reply i just posted to another thread as I understand the multimodal approach may be of interest... nice to meet everyone. I’ve learned a ton from this board.

- -

Schwah,

We’re in a very similar boat. I’m a very young guy (42) dx’d with Gleason 9 oligometastatic PCa, 3 bone mets - one in each hip and micro at t4.

DX’d in July w Psa at 2.5 jump from 1.7 end of May. Mild urinary symptoms. Self referred for Mri to private clinic on a hunch.

Medical curiosity. They suspected small cell, and a genetic mutation. First oncologist gave me a handshake and best wishes.

No genetic mutation (3 major screenings), adeno not small cell, and no circulating tumor DNA whatsoever. Also had PSMa pet within a month. Onc said yes bet this one will light up! Didn’t light up. Just the 3 mets.

Down to .2 after one shot of Zoladex and a month of bicalutamide.

I too found an oncologist at a major centre who subscribes to the kitchen sink for oligo theory and am doing a trial with definitive treatment intent.

On Docetaxel, Zoladex, Abiraterone (and prednisone) and zoladronic acid concurrently. Asymptomatic but I cry at random tv commercials now.

Halfway through chemo. Surgery is next. Then radiation to the bed with curative intent at 100gy and SBRT to the Mets.

All to be done within 9 Months. If any nonsense, Germany is next. Young kid, family devastated, top of corporate ladder, all the things.

Nice meeting y’all.

[Schwah]

I agree with it all. Hit it hard and hit it early. Keep us informed on your progress. This community truly cares.

Schwah.

[GP24]

Do what you can to avoid side effects. They say, rich men do not live longer, but they suffer from the side effects of the many treatments they are offered.

The dose of 100 Gy is very likely to cause bad side effects. If you have bone mets, radiating the prostate bed can have no curative intent.

[AlooGobi]

Thanks man. One step at a time. I have great support in a smart naturopath and I clear everything adjuvant through the oncs.

Halfway through chemo while on this systemic cocktail. I’ll worry about surgery next. Radiating the bed is part of the trial protocol for any positive margins / nodes. It’s sbrt for the Mets. Cheers.

[jdm3 in reply to AlooGobi]

Interesting. Thanks. Just curious to know what the naturopath has you on and doing in addition to the other stuff. Be well, Josh

[GP24]

A cytoreductive prostatectomy can provide benefit with limited side effects:

euoncology.europeanurology....

ncbi.nlm.nih.gov/pubmed/281...

[snoraste]

Glad you're on top of it. I'm undergoing an Oligo regiment as well. Did my PSMA scan in london (low avidity). I went the surgical route and took out the prostate and all lymph nodes in the vicinity just in case (I had one lymph node with positive margin). There's a lot of information on this site about the multimodal treatment (pros and cons). would be a good read perhaps. Hang in there - you're doing well

[Hirsch]

best of luck to you..

what kind of surgery do they propose to do?

[AlooGobi in reply to Hirsch]

Radical robotic

[Hirsch]

thanks good luck are you in uk or canada?

[AlooGobi in reply to Hirsch]

Canada, working with docs both locally and at Hopkins