RP in 2011, first recurrence and subsequent IMRT in mid 2015. Second recurrence (PSA .2) August 2017. I have not had any medication (hormones, chemo) in the 7 years I have been fighting. Learned this morning my PSA is now at .5 so I assume will be having the PSMA pet scan done at Hopkins Baltimore to try and find out where the PCA has gone. I assume I will then go to Zytiga, Prednisone and Lupron. I am choosing Zytiga because I think it is as effective and has fewer side effects than Docetaxel. Seeing my doc on the 19th and would appreciate any thoughts on this plan I have for my next step. Thank you!
Second Recurrence now at PSA .5 - Advanced Prostate...
Maybe, maybe not. It would depend upon detecting small mets in the pelvic LN area, which even with the best PSMA PET scans is difficult:
There is a trial of the DCFPyL PET at NIH, which may be able to find something. If so, it is important to irradiate as broad an area as possible, and not just treat what you can see. There may be limitations due to the previously irradiated area, but modern linacs should be able to not overlap the treatment zones substantially.
My husband's history.
Prostatectomy in Feb 2011 at 52 years old.
PSA undetectable until 2014, 0.5
37 sessions of radiation on prorate bed.
Unfortunately PSA continues to rise July 2017, 8.7
Axumin pet scan showed metastasis in 2 iliac lymph nodes in pelvis area.
September 2017, Firmagon( Degarelix) shots once a month, for 3 months. Zytiga 1000mg daily with 10mg Prednisone.
December 2017, switched to Lupron every 3 months. Even though his PSA is <0.1 he decided to do 6 rounds of Taxotere in January 2018.
Our prayers are for a long remission. I hope I didn't overwhelm you with all this info. My prayers for you. Stay strong.🙏