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Advanced Prostate Cancer
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Vitamin E - Tocotrienols

A new review paper below [1].

"Tocotrienols, analogues of Vitamin E have gained increased attention due to their safety and efficacy. Extensive research over the past several years has strongly indicated that tocotrienols can efficiently prevent/inhibit the growth of different cancers such as cancers of blood, brain, breast, cervical, colon, liver, lung, pancreas, prostate, skin, stomach etc. This is mainly accredited to their ability to modulate various molecular targets involved in cancer cell proliferation, survival, invasion, angiogenesis, and metastasis such as NF-κB, STAT3, Akt/mTOR, etc. In addition, increasing lines of evidence has shown that tocotrienols can sensitize cancer cells to chemotherapeutic agents such as celecoxib, doxorubicin, erlotinib, gefitinib, gemcitabine, paclitaxel, statin etc. Moreover, several clinical trials have confirmed the safety and tolerability of tocotrienols in humans. This review summarizes the potential of tocotrienols for the prevention and treatment of different cancers based on the available in vitro, in vivo and clinical studies."


[1] ncbi.nlm.nih.gov/pubmed/294...

2 Replies

Very interesting.!!!



With all the potential supplement that show promise (just like Tocotrienols), I’d be concerned with the various drug interactions. Would there be competing for the same targets/resources/receptors and if so, would the lesser effective of them win the prize, hence rendering the more effective drugs useless.

I think it may have been you mentioning Curcumin competing for AR with other targeted drugs.


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