PSA this time settled at 0.142 up from last one at 0.132 but less than the 0.148 time before. Plateau seems to have been reached and cumulative side effects are getting worse. Unless blood tests in three weeks show significant drop, we are done with Tatotere. Will continue Lupron and Xtandi for now. Then Bilateral Orchiectomy in a month or so. Then no more Lupron for life. If no more Chemo. monitor PSA for next 3 mo. and see what PSA is doing. Then whole new set of decisions to make for further treatment. Both of my DR's seem to think my levels are good but I wanted to push for 0.05 or less--not going to happen.
Doug
Written by
Shooter1
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Those are really excellent PSAs after the chemo, some of the best I've seen, in fact. You are getting a uPSA with too many decimal points for your condition -- what you are calling up or down or well within normal variations. Consider using a conventional PSA test in the future - it will give all the info you need with less anxiety.
9 sessions of chemo is a lot- a standard cycle is 6 infusions (3 weeks apart). I guess they pushed it because you didn't have serious adverse reactions.
Are you castration-resistant already? If not, consider holding off on the orchiectomy so you can have occasional vacations from Lupron.
Adding Zytiga is the new standard of care for this, and there are several good clinical trials for men in your situation that you might consider.
Don't worry about what exactly the PSA levels are. Enjoy your time off Chemo and until further decisions will have to be made. Who knows? Maybe the PSA stays this low and you don't have to do further treatment... We just never know... Best wishes from Dublin.
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