Began my 3rd round of chemo 3 weeks ago with same combo of Docetaxel/Carboplatin as the prior 12 infusions. This time Med Onc suggested we continue Xtandi, which had been used on a rechallenge basis after the prior 2 rounds of chemo, but NEVER during chemo.
Results were impressive. PSA dropped from 2.8 to .5 with this combination. Xtandi on pure rechallenge basis had brought PSA down from 48 to 2.8.
Combination of Xtandi and chemo gives me renewed hope for a durable remission if liver mets are positively impacted. Will know for sure in a couple of weeks with next liver MRI.
Best Wishes. Never Give In.