Chemo done after 4 infusions - Advanced Prostate...

Advanced Prostate Cancer

20,782 members25,887 posts

Chemo done after 4 infusions

Alvin735 profile image
12 Replies

It's been a rough go on Docetaxel and Carboplatin. Ended up in the hospital twice after infusions, pneumonia and then a high fever/rash. Now new rash all over is terrible, so Dr. decided to give me a break after 4 infusions and call it quits for the time being. PSA did go down to .8, so it was working, but the rash is very concerning. Glad to be on a holiday! Will be doing scans the middle of September and then we will see where we go from there.

Written by
Alvin735 profile image
Alvin735
To view profiles and participate in discussions please or .
Read more about...
12 Replies
NPfisherman profile image
NPfisherman

Sorry to hear you ended up in the hospital but .8 is a solid response. Did they give you prednisone for the rash?? Hope you feel better soon....

Don Pescado

Alvin735 profile image
Alvin735 in reply to NPfisherman

I'm currently on a daily .5 dose as I was on Zytiga before the chemo and onologist said to just continue the Dex. Rash is better after two weeks, but now I'm peeling all over. But, this too shall pass and I'm just glad I'm off the monster for a little while. I know everyone has different reactions, and I have had very few reactions on all the other things I've been on, so thought chemo would be a piece of cake ... it was not.

MelaniePaul profile image
MelaniePaul in reply to Alvin735

I am so sorry to hear you had to stop treatment. But September is not too far away and after scans you will hopefully have a better idea of what the next step could be.

I had never heard of this side-effect before, but perhaps it is your body's attempt to detox? Maybe the combo was too much for your body at the moment.

Anyway, please keep us posted!

Mel.

AlanMeyer profile image
AlanMeyer

I suggest also asking the doctor about lower dosages. One approach is to use the same schedule, e.g., one infusion every three weeks, but with a lower dose. Another is to have one infusion every week, but at only 1/3 the normal three week dose. I have heard anecdotal evidence that that can be just as effective but significantly reduces side effects.

Best of luck.

Alan

whatsinaname profile image
whatsinaname in reply to AlanMeyer

Yes, TMH in Bombay does just that. TMH= Tata Memorial Hospital.

Smaller doses but more infusions. Simple.

Apparently it works rather well.

Alvin735 profile image
Alvin735 in reply to AlanMeyer

After the scans in September, if PSA is going back up, I'll check on doing that. Thanks

Shooter1 profile image
Shooter1 in reply to Alvin735

After taxatere, while continuing on Xtandi, I shed the skin on my whole body. Looked like Pig Pen from comics, leaving a cloud of skin flakes everytime I moved. That too passed with lower dose of Xtandi.

henukit profile image
henukit

Sorry to hear about rough side effects. Were you treated with taxanes (docetaxel) before? Did you have significant side effects at that time? Whast is your protocol/dose for each drug? I agree, sometimes lowerg doses can work with less side effects.

Tall_Allen profile image
Tall_Allen

Some believe that a PARP inhibitor may work as well as a platin for BRCA2+. Perhaps it might be less toxic than adding the carboplatin. Here's a list of clinical trials where you can get a PARP inhibitor for BRCA2+:

pcnrv.blogspot.com/2018/02/...

Bebby1 profile image
Bebby1

My husband only tolerated two of six docetaxal

Hospitalised five times with neutropenia

Dr called it quits

Always high fevers but no rash

I hope it settles quickly and you can complete the course

All the very best

Greatfaith profile image
Greatfaith

Sorry to hear you had such a bad go, I guess I’m lucky that I’ve only felt tired & lost my sense of taste after 5 infusions. Hope you feel better every day. Hang in there brotha!!

Collarpurple profile image
Collarpurple

🙏

You may also like...

2nd chemo session done

just went through my second Taxotere infusion Tuesday. so far so 'good' I guess, no appetite and...

Update on Keytruda after 6 Infusions

and after the initial 6 infusions things are stable. When starting Keytruda my PSA was 34 after...

Lutetium-177 update after 2nd infusion

post scan was compared with the post scan from the 2nd infusion and most metastases on the bones...

2nd Round of Chemo Done

met with my onc and said after one round of chemo and one shot of Lupton, my PSA dropped...

Arterial chemo infusion