Hi, I'm writing for my Uncle who is 83 years old. He started Xtandi 2 months ago. About 6 weeks ago, he started to feel his back hurt and some leg aching. It does wake him up.
His PSA went from 7, to 14, to 25. He hasn't had a PSA test in a month. What becomes difficult is that I'm not monitoring his situation. He lives in another state. There could be a number of things converging at the same time. His daughter is very afraid of the pain, understandably.
My guidance to her is to get another PSA test immediately. See if his PSA is still rising. If so, I would suggest taking him off since he's experiencing a number of other side effects from this drug.
I also suggested that he get an MRI, first testing his kidneys for the contrast.
I'm concerned about heading off a compression fracture.
He wants to live, and is choosing to try whatever he needs to try. This is his choice and way.
At this point tylenol relieves the pain and discomfort.
I am going to question him to pin point the type of pain.
Have any of you experienced aching and pain from the Xtandi?
If it isn't working, this is the first to remove. Then get an MRI, see if he needs spot radiation on a vertebrae. He did have loose bowels this morning, which has to be watched because of the possibility of a compression to a nerve.