My father has Been on Xtandi, since September 20 2017. (3.5mo) his PSA is going up and his last reading was today 14. Sept 4.1, 6.44 and now 14!! I guess it’s not working and his cancer is not responding to it. Anyone else have this happen? What did your oncologist do? Take you off, or continue to try if it’s not working because maybe it needs more time to work? This is the highest it’s ever been since he has a radical prostatectomy in 2014..