Foods/Supplements-Vitamins: Phosphorus

Nalakrats recently provided a mineral ratio for bone health [1]. It included "500mg of Phosphorus". I have always assumed that most get plenty of phosphorus from their diets.

Wikipedia [2]: "The main food sources for phosphorus are the same as those containing protein, although proteins do not contain phosphorus. For example, milk, meat, and soya typically also have phosphorus. As a rule, if a diet has sufficient protein and calcium, the amount of phosphorus is probably sufficient."

As with excess calcium intake, phosphorus can suppress the conversion of vitamin D to its active hormonal form (i.e. calcidiol to calcitriol). For this reason, I have long warned about phosphates in soft drinks & deli meats, as well as the phosphorus in a 16 ounce T-bone steak (3-4 oz is OK).

A 2015 paper from Giovannucci [3] says it all.

"High calcium intake has been associated with an increased risk of advanced-stage and high-grade prostate cancer. Several studies have found a positive association between phosphorus intake and prostate cancer risk."

"We investigated the joint association between calcium and phosphorus and risk of prostate cancer in the Health Professionals Follow-Up Study, with a focus on lethal and high-grade disease."

"Phosphorus intake was associated with greater risk of total, lethal, and high-grade cancers, independent of calcium and intakes of red meat, white meat, dairy, and fish."

"Phosphorus is {a} mineral found in dairy foods, although it is more widely distributed in the diet than is calcium. Fewer studies have examined phosphorus intake and prostate cancer risk. We previously reported that higher phosphorus intake was associated with an increased risk of high-grade disease in the HPFS, independent of calcium intake [4]. Three other cohort studies have looked at phosphorus and prostate cancer; 2 found an increased risk with higher intakes, whereas another found a suggestion of a positive association. Whether the association for phosphorus is independent of calcium intake has not been fully investigated."

"Men consuming higher levels of total phosphorus were ... more likely to be Caucasian, were less likely to smoke, engaged in more vigorous physical activity, and reported more intensive PSA testing than did men consuming lower levels. Higher intakes were associated with somewhat greater supplement use, although to a lesser extent than was calcium. Men consuming the most phosphorus also consumed higher levels of calcium, supplemental vitamin E, and animal protein and lower intakes of alcohol and coffee. Men with the highest intakes of phosphorus were also more likely to be diabetic."

"Higher quintiles of phosphorus intake were associated with greater risk of prostate cancer (adjusted RR for quintile 5 compared with quintile 1: 1.12 ...)."

"In particular, higher intakes were associated with greater risk of lethal {+28%}, advanced-stage {+31%}, high-grade {+56%}, and grade 7 cancers {+17%}."

"Phosphorus intake was not associated with the risk of localized or low-grade cancer."

In 1998, Giovannucci was author of a paper [5]: "Calcium and Fructose Intake in Relation to Risk of Prostate Cancer"

"Ingestion of fructose reduces plasma phosphate tran

siently, and hypophosphatemia stimulates 1,25(OH)2D production."

"Fruit intake was inversely associated with risk of advanced prostate cancer (RR, 0.63 ... for > 5 versus < or = 1 serving per day), and this association was accounted for by fructose intake. Non-fruit sources of fructose similarly predicted lower risk of advanced prostate cancer."

i.e. the micronutrients in fruit were not responsible, since fructose itself had the same effect. For at least ten years, I have sweetened my morning coffee with fructose.

Kapur (2000) [6]:

"Low dietary intake of phosphorus leads to an increase in serum concentration of 1,25-(OH)2-D. In addition, dietary fructose reduces plasma phosphate levels by 30 to 50% for more than 3 hr due to a rapid shift of phosphate from extracellular to intracellular compartment."

IMO, not only is there no need to supplement with phosphorus, but there is benefit (with PCa) in having depressed blood levels for part of the day, in order that PCa cells might be exposed to calcitriol.

-Patrick

[1] "1000mg of Calcium, 500mg of magnesium, 500mg of Phosphorus, 99mg of Potassium, 50mg of Zinc, and 3 mg of Boron."

[2] en.wikipedia.org/wiki/Phosp...

[3] ajcn.nutrition.org/content/...

[4] cebp.aacrjournals.org/conte...

[5] cancerres.aacrjournals.org/...

[6] ncbi.nlm.nih.gov/pubmed/110...

4 Replies

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  • Patrick,

    I gave up cheese. However, I am glad I get to keep my apples, grapes and bananas. Perhaps, I will eat cheese once, every two weeks.

    Rich

  • Rich,

    I'd go for the full fat ('triple creme'). You will eat less, enjoy it more, & get far less of the IGF-I growth factor & other elements associated with the protein..

    -Patrick

  • Patrick,

    I will take your advice, and in two weeks try that cheese product. I had cheese last night at dinner at my lodge.

    Thank you,

    Rich

  • Patrick--I did not want to get into the long form of the bone health in terms of the first 3 minerals--Cal, Phos, Mg,---But the most important part of the protocol is the form of what you take. I.E, would you take calcium carbonate for your calcium supplementation, or would you take calcium citrate. Obviously you would take the citrate to avoid getting kidney stones and other health issues.

    As I said the ratio is correct, between all but for the [form of each], I did not in my recent post expound upon, as there would be a lack of chemists/nutrition healers, on this site. So let me expand on what each of the forms are, in:

    [1] The Calcium as[Calcium Hydroxyapatite, Citrate, Asparate, Alpha Ketoglutarate, Lysinate]

    [2] The Phosphorus as[ Calcium Hydroxyapatite]-Where is the Phosphorous Powder?

    [3] The Magnesium as[Magnesium Oxide, Citrate, Asparate, Taurinate, Alpha Ketoglutarate]

    As you can see the minerals above are in a very sophisticated CHELATED FORMAT, specifically designed to not cause problems with bodily systems and organs and to not interact with each other in a negative way.

    I can only attest to the fact that I have used this format, including the potassium, zinc and boron for 20 years. And at my last Bone Density study, done 3 weeks ago, at the age of 73, fully loaded up on ADH drugs---my relative age as to bone density was given to me as what they would normally see with a 25 year old athletic male. I can only conclude, using myself as the subject, that my bone density scores did not come from eating Hebrew National Hotdogs. Matter of fact I think I will treat myself--everything in moderation!

    Nalakrats

    P.S. anyone using the format of minerals I posted on will notice a 10-25% drop in their blood pressure---this assumes your blood pressure is high and you are not taking some pharmaceutical concoction to lower the blood pressure.