Nuts, Peanuts & Peanut Butter.

[pjoshea13]

New study fom the Netherlands, below [1].

"The consumption of nuts has been associated with a reduction of cancer risk, but only a few studies have examined the effects of nuts on prostate cancer risk. The current study prospectively investigated the association between the consumption of total nuts, tree nuts, peanuts, and peanut butter and the risk of total, advanced, and non-advanced prostate cancer."

"The association between nuts and prostate cancer was evaluated in the Netherlands Cohort Study, which was conducted among 58,279 men aged 55–69 year at baseline."

"For total, advanced, and non-advanced prostate cancer, no significant associations were found for total nuts"

"No significant associations were observed for tree nuts and peanuts for total, advanced, and non-advanced prostate cancer risk."

"Peanut butter consumption was associated with a significantly increased risk {+33%} of non-advanced prostate cancer .., but not with total or advanced prostate cancer."

It should be noted that not all peanut butters are made from 100% peanuts. Some have salt &/or sugar added. Some of the oil may be removed & non-peanut fat added. etc.

in 2016, I posted [2]:

"Foods/Supplements-Vitamins: Peanuts"

also [3]:

"Foods/Supplements-Vitamins: Nuts"

-Patrick

[1] nature.com/articles/s41391-...

[2] healthunlocked.com/advanced...

[3] healthunlocked.com/advanced...

[NPfisherman]

Thanks Patrick....I won't hold it against my nuts....LOL....or my almond butter...

Fish

[jdm3 in reply to NPfisherman]

Celery with freshly ground almond butter is our favorite snack.

[NPfisherman in reply to jdm3]

Heck yeah, I love that too... great on celery, rye wasa cracker, etc... sometimes, I cheat and have some sugar free blackberry jelly on it, but it is so darn good on that cracker that when I want a treat, I just can't help misbehavin'.... LOL...

[NPfisherman]

Nalakrats,

I guess that makes them Pro-Oxidant....may they break down, decay, and rot...

All the best,

Fish

[Hidden]

Don't take away my peanut butter!!!

[pjoshea13 in reply to Hidden]

I expect that you only eat the good stuff - 100% peanuts - but check the label. -Patrick

[Magnus1964 in reply to pjoshea13]

Absolutely, no salt, no oils, nothing. I can't stand the national brands, they all taste too salty to me.

[LeeLiam]

My understanding is that peanuts are not really nuts at all. They are legumes. Like soybeans, they grow underground. I believe most, if not all, nuts grow on trees. It seems strange, scientifically, to include peanuts in the same study with real nuts.

[pjoshea13 in reply to LeeLiam]

Yes, it's one of life's mysteries - like eggs being in the dairy section of supermarkets.

-Patrick

[bdriggers]

So it’s the additives to PB that increases the risk?

[pjoshea13 in reply to bdriggers]

It's a hypothesis that might explain why whole peanuts did not have that association.

-Patrick

[Graham49]

Looking at your previous posts, it appears that the nuts with the most good stuff and least bad stuff for PCa are Pecans and Pistachios?

[LeeLiam]

What, no walnuts?

renalandurologynews.com/pro...

[pjoshea13 in reply to LeeLiam]

The polyphenols may trump any adverse effects of the ALA.

-Pareick

[j-o-h-n]

Wanna make kids quiet for a while? Feed them peanut butter on white bread with no drinks.

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 01/30/2019 5:45 PM EST

[Break60]

Aw nuts!😂

[Adam10]

Hi pjoshea13

Would you kindly clarify which types of peanut butter the study referred to when it cincluded there was significant risk between consuming peanut butter and non-advanced prostate cancer (but not advanced prostate cancer).

What is it in the peanut butter that causes the risk - the type of peanuts? or is it the other ingredients? If we consumed organic peanut butter would that reduce the risk?

[pjoshea13 in reply to Adam10]

The study did not appear to have that level of detail.

Jif is a popular brand - perhaps because it is "reduced fat". This is from the label:

Ingredients

Peanuts, Corn Syrup Solids, Sugar, Pea Protein, Contains 2% Or Less Of: Salt, Fully Hydrogenated Vegetable Oils (Rapeseed And Soybean), Mono And Diglycerides, Molasses, Magnesium Oxide, Niacinamide, Ferric Orthophosphate, Zinc Oxide, Copper Sulfate, Folic Acid, Pyridoxine Hydrochloride.

There's a lot to object to, but particularly:

"Fully Hydrogenated Vegetable Oils (Rapeseed And Soybean)"

IMO.

If your brand is 100% peanuts, regardless of whether it is organic, I suspect that the risk is identical to eating whole peanuts - i.e. no risk, in this study.

-Patrick

[George71]

pjoshea13,

Someone on here said you knew of several PCa patients that take high dose testosterone -- I m interested in possibly try that before going the ADT route. What are they doing -- how much do they take and does it spike their PSA or seem to reduce or hold it steady?

[pjoshea13 in reply to George71]

George,

I can't say that I know men of who are using high T continuously. I have known men who have restored T levels, including one who was seeing Dr. Morgentaler.

Insurance coverage caused me to switch from a daily patch (AndroDerm 4 mg) to weekly injections of T cypionate. The injections cause an up-front spike.

My experience 12+ years ago when my T was >1,000 ng/dL was that PSA did not move in 6 monthly blood tests. & then I messed things up by injecting B12. But I had a long spell where PSADT moved from ~3 months to >24 months. Eventually, the PSADT began to shorten.

These days, I use T for rapid cycling between high-normal & castrate.

-Patrick

[George71 in reply to pjoshea13]

That is interesting -- given my profile -- do you think I should give high dose T a try? My T level is currently about 500 and I'm only taking Avadart, 2 years and 9 months post

surgery . Surgery 4/2016 post path. report -- negative margins except 4 of 10 lymph nodes micro. PSA was 0.03 -- and now 1/2019 is 0.7 slowly rising. negative f18 scan last Sept. One OC said wait till PSA is 5 then intermittent ADT -- the other said RT + 6 months ADT and Zytiga. Any thoughts?

[pjoshea13 in reply to George71]

George,

I usually think of high-dose T in terms of what Sam Denmeade is doing with patients on ADT (or what "Dr. Bob" Leibowitz does or did following triple blockade). The target T is near 2,000 ng/dL.

Your T is ~500. Would high-normal T - say 1,000 ng/nL - help you? I doubt that you'd see any benefit. Do you know what your estradiol [E2] is? Higher T might help balance E2:T if E2 > 30 pg/mL.

I can't address your last question.

-Patrick

[George71 in reply to pjoshea13]

My son said from his research that super high E (E2 patches) offsets and stops the production of testosterone -- in effect it works as similar to ADT -- and on the other hand he thinks that super high T turns to Estradiol -- but in the case of adding high T regularly you are still getting T. He said that the high E makes the body think it has high T and stops making T.

if true, It seems it would be better to add super high T rather than adding high E2 but I have not been able to find anyone other than you that has done anything like this. What were you doing with the T that worked so long prior to taking B12?

[pjoshea13 in reply to George71]

George,

It's hard to remember back 12 years or so, but I was taking a lot of polyphenols.

Throughout, I have been taking 0.5 mg Arimidex 3/weekly, to keep estradiol [E2] at about 20 pg/mL.

When you supplement with T, some can turn into E2. My concern though, has been that PCa cells tend to express aromatase (normal prostatic epithelial cells do not), which converts T to E2 for internal use. Blood tests don't tell you what is going on in those cells. PCa cells also over-express the alpha estrogen receptor [ERalpha]. So Arimidex is important IMO, to avoid estrogen dominance in those cells.

-Patrick

[Adam10]

Thanks Patrick. Reassuring that whole peanuts do not appear to pose any risk. I eat peanut butter on rice cakes every morning as a snack at the office. I avoid JIF peanut butter and similar like the plague. I willingly pay the extra to buy whole peanut butter. Thank you for your excellent posts.

[pjoshea13 in reply to Adam10]

Hi Adam,

On the other hand:

"Rice cakes can have a glycemic index rating as high as 91 (pure glucose has a rating of 100), making it the kind of carbohydrate that will send your blood sugar on a roller coaster ride."

shape.com/healthy-eating/di...

WASA rye crispbread might be better.

-Patrick

[Adam10 in reply to pjoshea13]

Thanks for the info Patrick.

I’ve been eating 6 slices of rice cake with peanut butter each morning and feeling I want to keep eating. Now I know why!

I have Hashimoto’s disease hypothyroidism as well as PCa so try to keep to a gluten free (GF) diet to keep the antibodies down (to reduce attacks on my thyroid).

I will look at GF crisp breads.

Thank you again for the excellent insights.