Lupron/Eligard and Atrial Fibrillatio... - Advanced Prostate...

Advanced Prostate Cancer

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Lupron/Eligard and Atrial Fibrillation Meds

WSOPeddie profile image
10 Replies

My urologist is suggesting an eligard shot before I start radiation treatment. I've seen warnings about interactions with heart arythmia medications, in my case propafenone. Has anyone experienced serious interactions between eligard/lupron and these heart meds? My cancer isn't advanced. Maybe I should just get the radiation and forget the chemical castration fun prior to the radiation?

10 Replies
Aussiedad profile image

No, go for it ...

WSOPeddie profile image

Thanks for the quick replies guys. 5 of 12 cores positive: a 6 a few 7's and an 8, so Gleason 8 it is -- aggressive. I am leaning toward radiation but will be getting a 2nd opinion on whether surgery is possible after prior TURP surgery 10 years ago. I wish there were a way to test my reaction to lupron/eligard before getting a 6 month shot. I'll be asking the 2nd urologist his opinion on all of these options too. Anxious to get going on treatment. The CT and bone scans were negative but I've heard of disappointing findings after that. This is a nice active board.

Jeff54 profile image

I have Atrial Fibrillation since 2008 and I am taking Multaq which is for my arrhythmia and have been on Lupron for 3 years and I have not had any problems! And I also walk Friday,Saturday and Sunday 2-3 hours steady on the beach every week! I hope this will help you.

BigRich profile image

You better check with your doctor, for Bicalutmide may interact with your medication. In fact, discuss with your doctor all medication interactions.

Good Luck, Rich

afab profile image

I have AFIB and metastatic PC; also have had a tissue valve replacement. I'm on metrororol, luprone and Xtandi. Things seem to be going ok other than typical fatigue from Xtandi. I was on propafonene before my cardiologist switched me to metrororol. Suggest you get a cardiologist consult before making a decision on whether there are any adverse drug interactions.

Wayne-P profile image

Hidden ,

What type of supplement program are you on?

yope4 profile image

I think what is crucial in treatment selection is the determination whether the Ca is local or metastatic. If it's local, either surgery or rad will cure the Ca without any additional treatment. Once it has metastasis, it has become a chronic disease. And unfortunately, scan technology is unable to detect micro mPCa. So your doc is guided by your test results which may not be complete due to undetectable micro mPCa as the case may be. Local case is curable, metastatic is not no matter that you threw the kitchen sink at it.

I say this from my own experience. After my rad treatment, my PSA went on a slow and steady rise. All scans before treatment and after my PSA had risen to 5.9 were negative. Finally, I underwent MRI with colorectal coil to hunt where the activity is. The result was a suspicious swollen lymph and it also showed no recurrence in my prostate. My prostate was basically fried. A biopsy was positive on the lymph.

I have since underwent ADT 3-month Lupron. From the 7.8 PSA I started with upon ADT treatment, it dropped to 2.0. And in the next 4

3-monthly checkups and treatments, my PSA was undetectable. My switch to an onc who is a specialist on prostate Ca was a turnaround. My onc will maintain my treatment since I appear to be in a class that responds well to the ADT with manageable side effects. And this is specific to the PCa type I have and the treatment chosen for me. I'm also hoping like the rest of us in this situation I hold it at bay, then, a treatment would come about that PCa no longer is factor to my life.

I don't know of any data that supports whether concurrent ADT to primary treatment extends survival with desired quality of life. And if your case is local, it's an over treatment which may affect quality of life if you happen to be in a class to get serious side effects from it.

And if your combined treatment is successful, would you end ADT. I believe data shows, if one has mPCa, it returns at some point after ending treatment. You would discover later than sooner that you have mPCa under a combined treatment. I don't know whether that's a plus or negative in a quest to beat down this disease.

Our journey in the case of PCa is complex and difficult for the fact that PCa can be undetectable while circulating in our system. Is it local or not I think is the big Q.

I wrote the above without any knowledge whether your heart med is a factor to ADT. If it's a major factor, I would discuss with my doc whether to look into additional treatment, such as ADT, if and when you have to cross that bridge. We're hoping you never would have to. Such as the nature of our beast.

My best regards to you.

WSOPeddie profile image

Postscript: it has been 4 months since my 6 month eligard shot. All is well with regard to my a-fib. No episodes since the shot. Thumbs up on eligard -- it wasn't a problem for me.

I just started dieting by not eating, and I find it quite not hard. I cheat often but not really much: sushi tuna, roast beef, salad bar salad, cottage cheese, even bran cereal. And water. I only say this because a lot of circulatory problems can be helped a good deal by reducing one's weight (pant size really). And the "Atkins" brand nutrition drink is good. I assume/hope that you are not still doing sugar. Best.

I also am a believer in Vitamin D, but I have not seen any tests that support it. Bruce Hollis is the guy that convinced me, but he is coming from the maternal breast milk angle. My 25OH is 80.

From 2014:

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