Happy new year to everyone! On the 28th December, I had my first Rituximab infusion. My consultant began by telling me my lumbar puncture came back clear and my flexible sigmoidoscopy showed mild Colitis, which he hopes the Rituximab will also treat. First I was given 100mg Methylprednisolone, followed by antihistamine and paracetamol & then the infusion began. Each half hour they checked my observations and increased the dose. My consultant told me to stop prednisolone for a week and restart it on Thursday, which is the same day he wants to review me. My second infusion should be on the 11th January. So far, I haven't noticed any severe side effects. I've had shakiness in my hands, though this started happening before the infusion. My consultant thinks it's a mixture of steriods/anxiety. I'm also struggling to get enough sleep and sleeping 3 to 4 hours at best. My palpitations haven't mproved much and continue to happen daily. I'm still feeling 'foggy' during the day and since stopping the steroids, my stools have become looser and paler. Today I had my second MRI to better assess the blood vessels in my head and neck. The scan was longer this time and a different dye was used. I should have the results in the next 10 days.