Does, intermittent prednisolone interact with l... - Thyroid UK

Thyroid UK

140,915 members166,036 posts

Does, intermittent prednisolone interact with levothyroxine?

Suegol profile image
8 Replies

I have chronic bronchitis and emphysema. I have had 5 chest infections in 5 months with prednisolone 30mg/day x 7 days x 5. I have never had so many infections. They take much longer to resolve. I take liquid levothyroxine as the tablets contain lactose and soluble prenisolone for the same reason. Any thoughts?

Written by
Suegol profile image
Suegol
To view profiles and participate in discussions please or .
Read more about...
8 Replies
PinkNinja profile image
PinkNinja

Are you noticing any changes when you are taking the steroids? It can affect how the thyroxine is converted to T3 but I couldn't say for sure. It might actually help in cases where cortisol levels are low. What you may find is that when you stop the steroid treatment, it might take a little while for your cortisol levels to get back up to normal (which is why it is important not to stop taking steroids suddenly). If this happens it can make you feel pretty awful and can result in inadequate conversion of thyroxine to the active T3. This is usually temporary and the adrenal glands do eventually kick back in.

Obviously you need to take the steriods for your lung conditions and shouldn't stop without the guidance of your doctor, but it could be affecting the way your body handles thyroxine on a short-term basis.

I expect someone else will have more information.

I hope you feel better soon. It sounds like you have a lot to deal with at the moment!

Carolyn x

I was on a similar course of prednisolone for bronchitis and asthma earlier in the year.I felt terrible on it and my GP realised that I would need to wean myself off it gradually-until i was on just 2.5 mg a day.It took me about a week after that to feel more myself.There is a warning on the leaflet that caution needs to be used for a person with hypothyroidism. I hope i never have to take it again!! Hope you feel better soon!

Hi had 2 lots of prednisolone earlier in the year for persistent lung infections, cant say i noticed any problems with it, was so glad to be able to breathe properly that i would have taken it regardless, It appears we all react differently to medication interactions, I try not to look too much into things or i tend to get obsessed, and i dont realy want my thyroid probs to be the only thing in my life ,hope you feel lots better soon x x x

prednisolone reduces you immune system and will make you more prone to infections. It may also affect thyroid function.

have you had you thyroid levels checked? Low thyroid will also result in reduced immunity.

Suegol profile image
Suegol

Thanks people, I will go back to the GP and relay this information. I have lung problems for many years and only thyroid function problems in the last 4 years. Still getting used to the interaction.

Heloise profile image
Heloise

Have you ever checked your vitamin D level? Infections are often a sign of deficiency.

In the future you might try taking n-acetyl-cysteine (NAC). Check it out for bronchial problems.

Suegol profile image
Suegol

Yes I have and take Vit D daily on the recommendation of my GP. Thanks for asking.

Not what you're looking for?

You may also like...

Prednisolone, levothyroxine and taking it with food

Had Prednisolone prescribed for 5 days (I am going to start on Sunday as at an event tomorrow night...
DeeFish71 profile image

Levothyroxine and Prednisolone

Morning Guys, I haven't posted for a while as my other health problems have been taking over. I was...
birthday1 profile image

Prednisolone

Hello Iv been given a 6 day course of this steroid and I'm a bit worried about taking it, hopefully...
dwsmith profile image

THS of 96.22 with 350mcg levothyroxine a day.

So ladies & gents, as my title suggests my current lab results are T3 1.9 - (2.8 - T4 6 - (9.0 -...
LornaP profile image

Moderation team

See all
RedApple profile image
RedAppleAdministrator
PurpleNails profile image
PurpleNailsAdministrator
SlowDragon profile image
SlowDragonAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.