I noticed almost immediately the improvement on T3 once the T4 was removed. When on the combined treatment I did not do well at all. My good endo allowed the removal of T4 to see how I did and allowed an increase up to 40mcg of T3. Paul Robinson explained about the dividing dose so split my tablets into 4 lots of 10mcg and the effect was amazing.
Once the T4 left my system which is about 6-8 weeks, I have had a prolonged period of feeling well. Have messed around with the dose to get optimal and I think I am pretty much there. I am able to do all the things I want (and loads that I don't want to!). For example yesterday, I have my little girl, 5, off school for easter. We cleaned up the kitchen thoroughly, did laundry and put it on the line, we went into the garden for 5 hours and dug and weeded as we are totally renovating the garden so this is more than it sounds. I came back in, made dinner from scratch and dessert, cleaned up and carried on for the evening. Before the T3 only I would have been able to maybe do the laundry whilst caring for my little one.
My schedule is:
11pm (or as I go to bed) 20mcg T3 to support adrenals - I sleep beautifully and not disturbed.
7am (or when I wake up) 20mcg T3
11.30am 20mcg T3
I also take supplements of Vit D, iron, magnesium, selenium, cod liver oil, multi vits, B12 and B vits. I was low in iron and deficient on Vit D.
My TSH is generally around 0.5 or less, my FT3 is around 3.5 to 4.1 (3.5 being the lowest range on the hospital scale), my FT4 is unmeasurable according to the hospital. My Dr is fine with these results as he can see I am healthy and do not go to the Drs unless it is for my yearly blood test (never used to go at all before all this thyroid stuff).
Does any of this ramble help?