I have just been to see my MD after having blood tests for Hypothyroid (yearly update) Chloresterol and HBA1c. My MD says that despite having 25g more thyroxine my Chloresterol has gone up. It's just hereditary she says. Can anyone tell me if high C can be caused in the process of losing weight? I was very pleased with myself because I have lost 2st since last year, which should have helped my chloresterol come down. I wondered if the liver disposing of the excess fat coult increase the blood chloresterol.