Graves disease fatigue

[Fastrun]

Hi

Thanks to everyone for the replies to my previous post. I have now had updated blood test results which the endocrinologist is happy with and is keeping me on 5 mg Carbimazole.

March test results:

TSH - 0.512 (range 0.27-4.2)

T4 - 16.8 (range 12-22)

T3 - 4.6 (range 3.1-6.8)

The first week post blood tests ( been on 5mgs for 4weeks) I started feeling much better generally but 2weeks further on (6 weeks on 5mg) and I am again really struggling with crippling levels of fatigue.

In addition to the 5mg Carbimazole I am taking Vitamin D as my previous results were low (41 nmol/l)

Endo didn’t say that my B12 or Folate were low although based on previous replies on the forum I have ordered the Igenuus B Complex tablets.

Any further advice would be appreciated. I am due back at work next week but not sure how I am going to manage this with the level of fatigue.

thanks

Fastrun

[SlowDragon Administrator]

Free T4 (fT4) 16.8 pmol/L (12 - 22) 

Ft4 48.0% through range

Free T3 (fT3) 4.6 pmol/L (3.1 - 6.8) 

Ft3 40.5% through range

previous post

healthunlocked.com/thyroidu...

Has endocrinologist ever offered block and replace?

Block with Carbimazole and replace with levothyroxine

[Fastrun in reply to SlowDragon]

Hi Slow Dragon

No he hasn’t mentioned that as an option. His plan is that I stay on 5mgs Carbimazole for another 8 weeks before a repeat blood test.

Thanks

Fastrun

[pennyannie]

Hey there again :

Your TSH bounced back into range in January 2025 - and can only repeat what I replied in your last post -

Your T3 and T4 are in range but ' low ' and you are dealing with both Graves and Hashimoto's and this crippling fatigue could be eased by switching to Block & Replace - thereby adding in a measured dose of T4 thyroid hormone replacement to increase your low T3 and T4 levels -

You could chop the 5mcg Carbimazole into 2 and see how you go at 2.5 mcg daily ?

[Fastrun in reply to pennyannie]

Thanks Pennyannie

Will consider that as an option.