Neutropenia: Took my last, hopefully, dose of... - Thyroid UK

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Neutropenia

tomh profile image
tomh
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Took my last, hopefully, dose of pred 3 weeks ago. I live in Brasil, and see a good, reputable Immunologist. Since I have had various ailments over the past dozen years, my initial treatment and 'follow ups' were in UK, and usual tracking of GCA markers, VHS and CRP, were invariably higher than recommended levels, since I had infections associated with other problems. The last 6 years, I basically ignored VHS, CRP results, and since GCA is not a symptomless disease, relied on signs of symptoms and physical checks for return of disease. Now to my main point. The first blood exam, following cessation of Pred, was after2 weeks. The Laboratory called me the day after the blood exam, wanting to know if I was having Chemotherapy. ! The Lab had a disturbing result on Neutrophils. Reading was 5%. 206/uL. The 'normal' range is 40-80% and 1800-7800/uL. I am 78 yo, male.

For 3 years I have had Hyperthyroidism, treated with Tapazol (tiamazol) when THS levels returned to normal, ceased Tapazol, and Hypo........ followed.

I was having 1.25mg Tapazol, every other day, as medication for Hyperthyroidism. The drug has known effects on Neutrophils, and I have ceased this medication. Endocrinologist wanted me to have radiation treatment on Thyroid, but I had a malignant Vocal Cord lesion laser removed 10 years ago, followed by 29 sessions of RadioTherapy. That surgeon recommended not to do Radiation treatment of Thyroid. Endicrinologist is now thinking of Radioactive Iodine therapy for Thyroid. She has, so far, been unable to contact Throat Surgeon. ( probably on Hols, Carnival Brasil)

Has anyone any experience of this. ?

I have retested to verify reading of netrophils.

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pennyannie profile image
pennyannie

Hello Tomh -

Have you been diagnosed with an Auto Immune Disease called Graves Disease and have proof of positive TSH Thyroid Receptors antibodies in your blood ?

Neutropenia can occur and is a common side effect of the Anti Thyroid medication -

and in the UK we have a second AT drug to try should this happen.

Do you have an option of a different AT drug ?

We do now have some research that may be of interest to you :-

pubmed.ncbi.nlm.nih.gov/338...

ncbi.nlm.nih.gov/pubmed/306...

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