Having a tidy up, I found my first Medichecks test results from November 2022.
My Thyroglobulin Antibodies were at >4,000 - now within range ( r 0-115) at 29.
Peroxidase Antibodies were 131 (r 0-34), now 50.5. So still elevated.
TSH is now 1.00 r 0.27 - 4.2. I was told that I started off at 58 but I haven’t seen that evidenced.
Still 75mcgs levo and feel mostly ok.
Is this of any import? I’m finally seeing GP this afternoon.
It’s very interesting to see how antibodies fluctuate so greatly. Having a positive results once confirms autoimmune.
In terms of treatment though the autoimmune aspect isn’t treated. Doctors replace low thyroid levels, hopefully including FT4 & FT3 not just TSH.
Hope your appointment goes well.
Thank you. It didn’t. I’m still processing it - but does ‘Don’t think so much’ sound like a good session?
Many Drs don’t understand antibodies. They say things like it’s a sign of developing issue in future.
Sorry to hear appointment didn’t go well.
😡😤😾🤬
I’ll repeat myself here, but in my appt after being left in 50 Levo for a year and obviously feeling horrible…
I talked about my continuing symptoms, that I track them, at which point he said - let me see.
I handed him my phone with the list of date/symptom that I had been keeping.
He looks, hands it back, waves his hand in a sweeping motion and says “Stop all this tracking…” I can still see his hand waving dismissively.
It was in that appointment where he wrote in my report “denies depression.”
The lack of knowledge is too much to be believed.
Medics are not taught anything about autoimmune aspect of Hashimoto’s
They just treat subsequent hypothyroidism
But you benefit from knowing the cause
Essential to maintain good vitamin levels
Hashimoto's affects the gut and leads to low stomach acid and then low vitamin levels
Low vitamin levels affect Thyroid hormone working
Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances.
Most common by far is gluten.
Dairy is second most common.
A trial of strictly gluten free diet is always worth doing
Only 5% of Hashimoto’s patients test positive for coeliac but a further 81% of Hashimoto’s patients who try gluten free diet find noticeable or significant improvement or find it’s essential
A strictly gluten free diet helps or is essential due to gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)
Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and may slowly lower TPO antibodies
While still eating high gluten diet ask GP for coeliac blood test first as per NICE Guidelines
nice.org.uk/guidance/ng20/c...
Or buy a test online, about £20
Assuming test is negative you can immediately go on strictly gluten free diet
(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially)
Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse
chriskresser.com/the-gluten...
amymyersmd.com/2018/04/3-re...
thyroidpharmacist.com/artic...
drknews.com/changing-your-d...
Non Coeliac Gluten sensitivity (NCGS) and autoimmune disease
pubmed.ncbi.nlm.nih.gov/296...
The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported
nuclmed.gr/wp/wp-content/up...
In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned
restartmed.com/hashimotos-g...
Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.
Similarly few months later consider trying dairy free too. Approx 50-60% find dairy free beneficial
With loads of vegan dairy alternatives these days it’s not as difficult as in the past
Post discussing gluten
healthunlocked.com/thyroidu...
Recent research in China into food intolerances with Hashimoto’s
healthunlocked.com/thyroidu...
More interesting Chinese research on Hashimoto’s and leaky gut
nature.com/articles/s41598-...
Thanks, as ever.
It is important to know that you have Autoimmune Thyroid Disease, yes, because of the way it affects you. It is not important to know the actual numbers because the fluctuate all the time.
You need to know if they are positive because one positive result means you have it. The fact that they then reduce to being in-range does not change the fact that you have it. Antibodies tend to be highest during an immune system attack on the thyroid when they have a job to do cleaning up the blood. Once their job is done, they reduce in number until the next time.
Antibodies are the result of the disease, not the cause, so their numbers don't affect the disease in any way. 
I have had antibodies as high as yours. I am hoping my next blood test will show they have reduced but I doubt they will have. At first I was alarmed by how high they were but after 10 years I have now accepted that I might always have high antibodies
Antibodies blood tests.
Anti-thyroglobulin antibodies
Antibodies
My Thyroid test results
