Overmedicated 2: Hello everyone, sorry if I didn... - Thyroid UK

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Overmedicated 2

Dearhound profile image
12 Replies

Hello everyone, sorry if I didn't reply to all your questions. I got dragged into Bath on Friday by my daughter to do christmas shopping ( completely wore me out). Just to let you know gp rang me eventually and prescribed 75mcg, daily, blood test in 8 weeks and eeg to check out my racing heart. So will see where I go from here. I just want to say thankyou to everyone who replied (I don't think I've been heard like this all my life) Your support was greatly received. Your advice, information has given me much food for thought on my thyroid path. To minimol, well spotted that was a typo it should have said ft4 8.7 not 7.44.and to slow dragon, I have aortic regurgitation. My main problem is that I suffer from tmj and burning mouth syndrome, which I was hoping Levothyroxine would calm down. Unfortunately it's got worse, but maybe that's a result of being over medicating, and my body stressing out and me grinding my teeth more. Anyway, thankyou, and Happy Christmas xxx

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TiggerMe profile image
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SlowDragon Minimol

SlowDragon profile image
SlowDragonAdministrator

TMJ is common hypothyroid issue

Have you got a mouth guard?

Having a mouth guard made at dentist, not cheap but lasts for years and can make an astonishing difference

My own mouth guard at least 20 years old…..I was highly sceptical when dentist persuaded me to get one …..thought I would only wear it for one night…..but been wearing it every night ever since

Dearhound profile image
Dearhound in reply toSlowDragon

Hi have got a mouth guard, but haven't stuck with it, because it feels weird, will have to give a better go.

SlowDragon profile image
SlowDragonAdministrator

which brand is your 100mcg

When reducing to 75mcg …… ideally stay on same brand

Perhaps initially reduce by 12.5mcg for first few weeks (75mcg and 100mcg alternate days ) …..see how that is before reducing to 75mcg daily

Burning mouth and hypo

pmc.ncbi.nlm.nih.gov/articl...

Dearhound profile image
Dearhound in reply toSlowDragon

First two months I was prescribed accord, last month Tevo. not sure what I've been prescribed next, Pharmacy closed over weekend, will pick up Monday.

SlowDragon profile image
SlowDragonAdministrator in reply toDearhound

Teva badly upsets many people

Have you found symptoms worse since changing brand ?

Many people find Levothyroxine brands are not interchangeable.

Most easily available (and often most easily tolerated) are Mercury Pharma or Accord

Mercury Pharma make 25mcg, 50mcg and 100mcg tablets 

Mercury Pharma also boxed as Eltroxin. Both often listed by company name on pharmacy database - Advanz

Accord only make 50mcg and 100mcg tablets. Accord is also boxed as Almus via Boots, 

Wockhardt is very well tolerated, but only available in 25mcg tablets. Some people remain on Wockhardt, taking their daily dose as a number of tablets 

July 2024

Crescent levothyroxine. Dosages: 12.5, 25, 50, 75, 100

(Not yet known if all approved dosages are or will be available).

Excipients: lactose monohydrate, maize starch, croscarmellose sodium, gelatin and magnesium stearate.

Lactose free brands - currently Vencamil or Teva

Vencamil is lactose free and mannitol free. originally only available as 100mcg only, but 25mcg, 50mcg and 75mcg tablets became available Sept 2024

Prior to March 2023 Vencamil was called Aristo

Vencamil often very well tolerated/best option for many people

How to get Vencamil stocked at your local pharmacy

healthunlocked.com/thyroidu...

Posts discussing Vencamil

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu....

Teva makes 12.5mcg 25mcg, 50mcg, 75mcg and 100mcg

Many patients do NOT get on well with Teva brand of Levothyroxine.

Teva is lactose free, but contains mannitol as a filler instead of lactose, which seems to be possible cause of problems. Mannitol seems to upset many people, it changes gut biome 

Helpful post about Teva

healthunlocked.com/thyroidu...

Posts that mention Teva

healthunlocked.com/search/p...

Teva poll

healthunlocked.com/thyroidu...

Relatively new ……Hillcross brand

This is a box, rather than a brand. 50mcg and 100mcg are Accord brand….but beware 25mcg is Teva brand

Helpful post about different brands

healthunlocked.com/thyroidu...

List of different brands available in U.K.

thyroiduk.org/if-you-are-hy...

Once you find a brand that suits you, best to make sure to only get that one at each prescription.

Watch out for brand change when dose is increased or at repeat prescription.

Government guidelines for GP in support of patients if you find it difficult/impossible to change brands

gov.uk/drug-safety-update/l...

If a patient reports persistent symptoms when switching between different levothyroxine tablet formulations, consider consistently prescribing a specific product known to be well tolerated by the patient.

academic.oup.com/jcem/artic...

Physicians should: 1) alert patients that preparations may be switched at the pharmacy; 2) encourage patients to ask to remain on the same preparation at every pharmacy refill; and 3) make sure patients understand the need to have their TSH retested and the potential for dosing readjusted every time their LT4 preparation is switched (18).

And here

pharmacymagazine.co.uk/clin...

Discussed here too

healthunlocked.com/thyroidu...

Dearhound profile image
Dearhound in reply toSlowDragon

Thanks for the info, your better informed than any doctor I k ow. Been going through this with my epilepsy meds. Apparently all the same. Category 2 meds. Different brand every mo nth. But when I was prescribed DrReddy brand, it just didn't work. Maybe I just distrusted the nam.e haha xx what a mindfield!

SlowDragon profile image
SlowDragonAdministrator in reply toDearhound

Are you taking Levo well away from all other medications

Dearhound profile image
Dearhound in reply toSlowDragon

Yes I am, wake up take levo, then water, maybe an hour later have earl grey rooibish, then 4 hours later, maybe coffee, but I am aware caffeine, calcium and iron affect absorption. I take lacosamide at night. Find it quite hard my life is governed by my medication, but I suppose I'll get used to it, only 3 months in.

Catlover1981 profile image
Catlover1981 in reply toDearhound

I am with you. I am getting used to taking a new medication and to help me remember to take it i have an App on my phone that gives gentle reminders to take it

BorzoiGalgo profile image
BorzoiGalgo

Off topic, but, do you have a deerhound? I ask, because I have several borzoi and a galgo.

humanbean profile image
humanbean

My main problem is that I suffer from tmj and burning mouth syndrome

Have you had your nutrients tested recently? I'm speaking about vitamin B12, folate, vitamin D and ferritin (iron stores). If you have recent test results could you post them and their reference ranges. And tell us what you are supplementing with, at what doses, and what the supplements actually contain.

There are some people who find their TMJ and mouth problems reduce in severity if their B12 and folate levels are optimal. It is not guaranteed to help everyone, but it is well worth the effort to optimise what you can.

Another factor is that if you are already supplementing that people sometimes only respond to supplements in certain forms. This is definitely true of B12 and folate. I got no improvement from cyanocobalamin and folic acid but benefitted a lot from methylcobalamin and methylfolate.

Doctors are not trained in nutrition, so they have little clue about vitamins, minerals and dosing. (My cynical mind says that the lack of training is deliberate - Big Pharma doesn't want people being kept well or getting better with vitamins, they want people to take medicines that make a profit.)

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