Has Anyone had an Experience With T2 Supplements - Thyroid UK

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Has Anyone had an Experience With T2 Supplements

Me1157 profile image
9 Replies

Could this be my missing link, as I have all the symptoms listed below? Or is it just marketing hype? I am looking for advice from my more knowledgeable friends on here! I had never considered this before, had you? It's a long post, as I've added most of what they say on their website about it! It's available in USA, and one of my friends sent it to me; wondering if this could help.

I'm booked for new complete thyroid tests with Medichecks on June 8, 2023. I switched meds from amour back to levothyroxine in mid-January after twenty-plus years on amour. The dr. said there had been many advances in levothyroxine over the years, and perhaps this would be a better medication for me now....I'll have been on levo for almost 5 months when I get my blood tests done again...Honestly, I feel worse... tired a lot, weight gain, and my sleep hasn't been good. but I was determined to give it a go.

Here's what they say:

Essential T2 contains bioidentical T2 thyroid hormone designed to provide your body with an exact replica of the same T2 thyroid hormone it would create in a healthy state. This supplement can help you create a more comprehensive thyroid hormone replacement regimen that mimics what the body produces naturally. Each capsule provides 100mcg of 3,5 Diiodo-L-Thyronine.

Taking Thyroid Medication? Use T2 Thyroid Hormone For a Complete Thyroid Profile

T2 thyroid hormone is the only thyroid hormone available over the counter and is something most thyroid patients don’t even know exists.

This is unfortunate because T2 thyroid, if used correctly, can provide your body with benefits you can’t get elsewhere.

And because very few medications contain T2 (only NDT formulations contain a small amount), it’s something that most thyroid patients simply aren’t getting enough of.

When your thyroid gland is healthy, it naturally produces T2 thyroid hormone along with the others you already know about, including T4 and T3.

The body creates T2 by converting T3 into T2 and we already know that many thyroid patients don’t have enough T3 at baseline because they can’t convert T4 into T3.

How do you expect to create T2 when you aren’t creating enough of the thing you need to make it?

You won’t be able to!

When you are in a hypothyroid state, when you are taking thyroid medication, or when your thyroid has been removed, ablated, or damaged as in Hashimoto’s, your thyroid is no longer able to produce this important hormone effectively.

T2 supplements provide you a way to put back in the thyroid hormone that your body can’t produce and bring you back closer to a state of healthy thyroid function. 100mcg of 3,5 Diiodo-L-Thyronine

It gets even better, though.

T2 thyroid hormone can be used with all thyroid medications and all thyroid supplements.

And because it’s a unique ingredient, there’s a very small chance (pretty much zero) that you are getting it from another source.

Why is T2 so important? Check out how it works in your body:

Benefits of Essential T2

While there is still more to learn, we know that T2 thyroid hormone is not some inactive thyroid hormone as we originally thought.

Doctors and researchers used to believe that T2 thyroid hormone was just a byproduct of thyroid hormone metabolism.

When your body was done using T3 and T4 it would create T2 as a byproduct which would then get recycled by the body.

We now know that this isn’t the case.

Not only does T2 perform its own functions, but it also helps T4 and T3 thyroid hormones work more effectively.

Here’s how it helps your body and thyroid:

Regulates basal metabolic rate

Activates detoxification enzymes in the liver

Activates brown adipose tissue

Increases cellular ATP production

Regulates cholesterol production

Assist muscles in burning fat and maintaining muscle health

Protects kidney function

Assist in the regulation of blood sugar

Help determine muscle tone

100mcg of 3,5 Diiodo-L-Thyronine The Complete Ingredient List: 1 Capsule Contains the Following

Other ingredients: Capsule (hypromellose and water), microcrystalline cellulose, Fu-Flow Rice Fiber.

Directions: Take 1-2 capsules daily, in the morning, on an empty stomach. If used with thyroid medication, take 30-60 minutes before or after. Storage: Keep closed in a cool, dry place out of reach of children. Does not contain: Wheat, gluten, dairy, soy, GMOs, or yeast.

Essential T2 features a synthetic source of T2.

Thyroid patients sometimes assume synthetic thyroid hormones are automatically bad just because they are synthetic but that isn’t the case. All thyroid medications are bioidentical, where they differ is the source.

Natural Desiccated Thyroid medications are considered “natural” because they come from animals (usually pigs). But just because something comes from animals doesn’t mean it’s automatically safe, either! We know from studies that horse hormones, for instance, can cause problems in humans.

We also know that animal proteins (such as those found in NDT) can exacerbate and flare up the immune system in humans. What’s more important than the source is whether or not the hormone is bioidentical and Essential T2 contains bioidentical T2 thyroid hormone.

Yes! Essential T2 can be used with other thyroid medications but should not be taken at the exact same time. And, just like other thyroid medications, you will want to treat T2 thyroid hormone in a similar way. That means taking Essential T2 on an empty stomach, away from food and drink, and at least 30-60 minutes away from other supplements and medications. It is also likely that T2 thyroid hormone will help both T4 and T3 thyroid medications work more effectively.

In a healthy state, your thyroid would produce T2 continuously throughout your life. This is not the case in many hypothyroid patients, though, so Essential T2 replaces that lost thyroid hormone via supplement form.

Unfortunately, right now there isn’t a readily available way to test your free T2 level. The testing for T2 exists but right now it’s primarily used for research purposes.

Even though you can’t directly test your T2 level, there are still ways to indirectly assess whether you have enough. Here are a few:

#1. You can estimate your T2 level by looking at your T3 level. This works because the major source of T2 in the body is from T3 to T2 conversion. If your body is low in T3 then you know you lack the substrate to make T2.

#2. You can look at proxy measurements of your metabolism such as your resting heart rate and basal body temperature. These are not perfect measures of your metabolism, but they can track with your thyroid status (but not always).

#3. You can look at your thyroid symptoms. If you are still experiencing low thyroid symptoms even while taking thyroid medication (and other factors have been ruled out), then it’s likely your thyroid hormones are not optimized. In a perfect world, you should optimize T2 levels like you would optimize T4 and T3 levels.

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helvella profile image
helvellaAdministratorThyroid UK

If you do a search, there are over 150 posts here which refer to T2. (Some might well be wholly irrelevant but a considerably number are good hits.)

healthunlocked.com/thyroidu...

The attached image and a long article are available here:

The basics of thyroid hormone action, transport and conversion

thyroidpatients.ca/2019/11/...

I cannot understand why you would need 100 micrograms of T2 when it is being taken to replace converted T3. (No mention of rT3 in your post so I'm ignoring that route.)

T2 is lighter than T3.

T3 molecular weight = 671.949

T2 molecular weight = 545.045

Thus it takes 123 micrograms of T3 to produce 100 micrograms of T2.

Virtually no-one takes or produces that much T3. But I see no explanation as to why this apparent over-replacement of T2 is seen to be necessary?

(In turn, that would require 100% perfect conversion of 147 micrograms of T4 to T3 for those on LT4-only. Or somewhere in between if they have some thyroid function. But it is usually assumed only a fraction, a third, a quarter, of T4 is converted to T3.)

Note: T2 is important. But I am not convinced of the arguments in the article.

Thyroid hormone deiodination molecular diagram
Me1157 profile image
Me1157 in reply to helvella

Thank you for your reply. I've checked out the posts!

Lulu2red profile image
Lulu2red

I have bought this exact product. I take T4/T3 now added 100mg T2 once a day. It's only been a few weeks but my constant low back ache has resolved, I am beginning to lose some weight, my bone pain and muscle pain much less. It's early days but looking good so far. T4 is no good for me as I have a gene problem so can't convert adequately. I just decided that I probably don't convert much T2 either so giving it a go. I believe if you cannot regain your health on T4 alone you need the full spectrum of thyroid hormones. I have so little thyroid function left now I have decided to replace what I can. T3 definitely helped with brain fog and swelling/ water retention mucin. I only take T4 now just to have a little in my body as there are receptors for it in the heart muscle but too much of it just turns into RT3 in my case so only take 50mg. If you decide to try T2 take it away from everything else you have to take or it won't work. Found that out quite quickly. Frankly you need to get your doctor to put you back on Armour. Best wishes 🙏

Me1157 profile image
Me1157 in reply to Lulu2red

Thank you

helvella profile image
helvellaAdministratorThyroid UK

The forum guidelines refer to "UK prescription only medications". But this clearly needs to be interpreted in the light of reality. For example, there is no UK prescription desiccated thyroid but that doesn't mean that it is OK to post links to suppliers of desiccated thyroid. Indeed, think back a short while to the time when it appeared that liothyronine might actually disappear. If there were no UK products, it wouldn't suddenly have been something for which it would be OK to post sources.

Similarly, if T2 were an authorised medicine, there is next to no doubt it would be prescription-only. And we would consider it in that light.

Also, please would you have a read of this post?

And me too...

healthunlocked.com/thyroidu...

Litatamon profile image
Litatamon in reply to helvella

Thank you for the guidance helvella.

helvella profile image
helvellaAdministratorThyroid UK

Because all we are getting are "Me too" replies requesting Private Messages (Chat) identifying sources, I am closing this post to replies.

This is despite adding the reply below to many of these replies.

Please would you have a read of this post?

And me too...

healthunlocked.com/thyroidu...

I'll also be deleting all the Me too replies.

Me1157 profile image
Me1157

Sorry, I have no idea where to get T2 from. I put up this post to see if anyone does take it and what experiences they've had with it.

helvella profile image
helvellaAdministratorThyroid UK

The forum guidelines refer to "UK prescription only medications". But this clearly needs to be interpreted in the light of reality. For example, there is no UK prescription desiccated thyroid but that doesn't mean that it is OK to post links to suppliers of desiccated thyroid. Indeed, think back a short while to the time when it appeared that liothyronine might actually disappear. If there were no UK products, it wouldn't suddenly have been something for which it would be OK to post sources.

Similarly, if T2 were an authorised medicine, there is next to no doubt it would be prescription-only. And we would consider it in that light.

The ability to reply to this post has been turned off.

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