These studies used T3 to benefit everything from mental issues, to gastrointestinal problems, to infertility, to poor performance in school. One study even used T3 with one-year-olds. Pretty remarkable results.
I've included links for each study.
- Tittle (1956). Effects of 3,5,3’ l-triiodothyronine in patients with metabolic insufficiency. sci-hub.ru/10.1001/jama.195...
- Kurland, G.S., Hamolsky, M.W., and Freedberg, A.S. (1955). Studies in non-myxedematous hypometabolism: I. The clinical syndrome and the effects of triiodothyronine, alone or combined with thyroxine. sci-hub.ru/10.1210/jcem-15-...
- Freedberg, A. S., Kurland, G. S., & Hamolsky, M. W. (1955). Effect of L-Tri-Iodothyronine Alone and Combined withL-Thyroxine in Nonmyxedematous Hypometabolism. sci-hub.ru/10.1056/NEJM1955...
- Kearns (1957). Liothyronine (L-triiodothyronine) as a substitute for desiccated thyroid. ncbi.nlm.nih.gov/pmc/articl...
Just reading this one tpauk.com/downloads/EUTHROI... (goldberg, case for euthyroid hypometabolism) which has a good few paragraphs about the use of the 'Lawson Kinemometer' for performing the ankle reflex test .
Starting on page 483 ~ "The simplicity and economy of the Lawson Kinemometer makes it a utilitarian device for use in the clinic....... "
It's a shame there isn't still a kinemometer in modern GP's toolkit .
When i was diagnosed in 2003 my GP had a go at assessing the speed of mine by eye, which was interesting, and led him to order further tests that led to diagnosis.. but obviously not very accurate by eye .
Typing " Lawson kinemometer tracing " into 'a search engine' produces some interesting stuff about tendon reflex testing in hypo / hyper / euthyroidism ..... eg. this one : pmj.bmj.com/content/postgra...
POSTGRAD. MED. J., (1965), 41, 518 A CRITICAL EVALUATION OF THE TENDON
REFLEX MEASUREMENT AS AN INDEX OF THYROID FUNCTION
A. M. ROBSON, M.D. Ncle., M.R.C.P. Luccock Research Fellow
R. HALL, M.D., B.Sc., Durh., M.R.C.P. Wellcome Senior Research Fellow in Clinical Science
and Honorary Lecturer in Medicine
G. A. SMART, M.D., B.Sc., Durh., F.R.C.P. Professor of Medicine The Department of Medicine, University of Newcastle upon Tyne
"It is now accepted that the tendon reflex is prolonged in patients with hypothyroidism.
Chaney (1924) was the first worker to record the Achilles tendon reflex and prove what had
previously been detected clinically. Since then several systems have been devised for recording the ankle jerk....."
"Despite its limitations, the technique can be helpful in the diagnosis of hypothyroidism and it is especially useful in assessing 'the effect of treatment and in regulating the dosage of thyroid replacement therapy given to hypothyroid patients."
First time i've seen mention of it's utility/ accuracy for assessing dose. ( *note the dose sizes of levo they were using at this time ... "don't feel better on 300mcg .. ok, have 400mcg" )
They found some link to hypEthyroidism too (speeded up , as opposed to slowed down) , but not in everyone.... hence their "...despite it's limitations" comment ........ but i strongly suspect this speeding up when hyper would have held true for me , because when was overmedicated with thyroid hormone , i was literally 'jumping' in response to unexpected noises in the street.
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