Thyroid hormone journey: Metabolism

[helvella]

For anyone who is trying to understand things like T4:T3 conversion, the deiodinase enzymes, how thyroid hormones move round the body and into cells, and so on.

Make sure you have plenty of time undisturbed. It is very long!

Follow the link.

Read - slowly.

Thyroid hormone journey: Metabolism

● The place of metabolism in the thyroid hormone journey

● Transport comes before metabolism.

● The basics: What are deiodinases?

● How do deiodinases convert hormones?

● Terminology and concepts for deiodinases

● Thyroid hormone ring names, iodine positions, and symbols

● The function of each deiodinase

● Deiodinase locations in the human body

● One enzyme type per cell

● Deiodinase locations within the cell

● How deiodinases co-regulate thyroid hormone signaling

● What can go wrong with deiodinases?

● Final big picture: Beyond the deiodinases

● Scientific thyroid pathway maps

thyroidpatients.ca/2021/01/...

The first review comment says this:

This epic, monumental article by Tania Sona Smith is amazing. Everyone should read it, immediately!

[DippyDame]

Hail Tania!!

[Hidden]

thank you for sharing!!! ❤️❤️

[pennyannie]

Guessing the conclusion is longer than the M1 -

I'll give it a go but might turn off at the first exit -

Thank you :

[Gingernut44]

Thanks, a little light reading when my brain is in gear. Perhaps we should send it to all GP surgeries in UK.

[Tythrop]

Will invest time .and thanks

[helvella Administrator]

An area of uncertainty and some disagreement.

I have seen someone improve within minutes of taking some desiccated thyroid. But it is necessary for there to be sufficient on a continuous basis for real, lasting improvement.

There has been insufficient research into the detailed processes. And there is also the problem that the first impact is more likely to be from the T3 content than the T4.