For those who have taken both Thyroid S & other brands of NDT

[Litatamon]

Curious, did you take the exact same dosage? Felt that the doses were relatively equivalent between the two?

If not, can you please post the differing amounts.

Thank you

[helvella Administrator Thyroid UK]

Obviously, this is just the claimed potency! But this shows that even if every product was exactly as potent as claimed, there would be a small difference.

Hormone content of desiccated thyroid products

[RedApple Administrator in reply to helvella]

Just for clarification, is this a chart you made or picked up from somewhere?

[helvella Administrator Thyroid UK in reply to RedApple]

I created it - it is in my Vade Mecum document!

[Litatamon in reply to helvella]

Thank you helvella.

[Imaaan in reply to helvella]

For doing this, I thank you Mr.

[Litatamon in reply to helvella]

Helvella can you explain the last two columns a bit, for me? Thank you

[helvella Administrator Thyroid UK in reply to Litatamon]

Many doctors criticise desiccated thyroid because it has a different ratio of T4 to T3 to that of humans. All too often, the claim is that is has too much T3.

Doctors, misguidedly in my opinion, argue that the ratio of T4:T3 should be 15:1, 10:1 or some other number.

I have calculated the ratios and put them in the table.

Doctors start out by calculating the ratio in terms of weight. That is what the first column is.

But T4 is heavier than T3. If you took 100 micrograms of T4 and converted it, perfectly, into T3, you'd only have 84 micrograms of T3! (The difference is the iodine atom that has been removed from each T4 molecules.)

The second column is calculated on that basis. Effectively the ratio of T4 molecules to T3 molecules.

If that makes no sense, just ignore that column. It doesn't make much difference.

[Litatamon in reply to helvella]

But it is is so interesting!

Thank you.

Helvella, do you know if NDT has ever had a weight ratio calculation ike levothyroxine (ie. 1..6 x weight on kilograms).

Say someone had a thyroidectomy, and wanted to immediately go on NDT (I know fat chance of that happening!). How would a replacement dose be judged, just as a starting point? As I assume it does not have a weight calculation.

[helvella Administrator Thyroid UK in reply to Litatamon]

Well, I am one of those who is very unimpressed by the "dose by weight" approach - for thyroid hormones.

We see people on doses from 25 to 300 micrograms of T4, from 5 or 10 to 150 of T3, or possibly even greater differences. And it most certainly isn't body weight that makes the difference.

Body weight is one factor. All other things being equal, a heavier person would need more. But that falls over because not all other things are equal! How well we absorb. How much weight is fat, how much muscle, etc. How well we process and circulate thyroid hormones in our bodies.

But, in your suggested situation, I might think of one grain possibly being somewhere near 75 micrograms of T4. Work that out. And start a bit lower.

[Litatamon in reply to helvella]

Thanks again. Appreciate all the insight helvella.

[Imaaan in reply to helvella]

Its interesting you say this. The Erfa phamplet said that 30mg was equivalent to anywhere from 50-100mcg of T4. It didnt end up that way for me. I'm around 45 kg and ended up needing around 235mg of Erfa. I was previously on 75mcg of T4 and it took my free t4 at the high end of the range .

My doc thinks its because of digestive issues.

[Litatamon in reply to Imaaan]

Four grains Imaaan?! A la just under 4 X 60 mg.

Wow such interesting & helpful information.

[Imaaan in reply to Litatamon]

Sorry it was a typo, I meant 135mg which is 2 grains and a quarter. Plus I take 6.25 mcg of Synthroid

[Litatamon in reply to Imaaan]

Whew.

[Imaaan in reply to Litatamon]

Lol... chalk it up to my sleep apnea and hypothyroidism

[Brightness14]

After having my Thyroid removed I started on Levo for the first time. Within 6 months I had put on weight and felt very ill. I then joined this site and started on Thyroid s I took a blood test after six weeks and my FT3 was slightly over range. For seven years I have been on the same dose 2.25 grains per day split 1.25 at 6am and 1 at 1.30pm I have felt well and my blood test results have always been perfect. When covid was going on I had to go onto Armour and when taking the same amount I found that it was much weaker in effect than the Thyroid s. luckily it was only for a few months.

Since than I have had trouble with my batch of thyroid s this year which was very weak but now starting on a new batch it seems to be working fine.

[pennyannie in reply to Brightness14]

Well that's good to read - maybe post the batch number of the latest bottle that appears to be ok so others can feel more secure with their purchases ?

[Litatamon in reply to pennyannie]

She has just started TA22012, I believe your next batch pennyannie, correct?

It is the one that I am on. And although my labs are not optimal I have felt positive changes (First time on Thyroid S or any NDT, so nothing to compare)

However another member on here flagged that batch, at some point strangely enough. I just don't remember their handle to get further information.

[Imaaan in reply to Litatamon]

I thought she had issues with that number? Pretty sure she mentioned it but maybe I'm way off

[Litatamon in reply to Imaaan]

Just went back to my thread and took it directly from there - Brightness mentioned that she had just started, two days in at the time, on TA22012. But I shouldn't add to the confusion and let her answer herself.

[Imaaan in reply to Litatamon]

Well dang it, my memory shouldn't be relied on..lol

Merci for letting inquiring minds know.

[Litatamon in reply to Imaaan]

Brightness' poor batch was TA22006, as per her thread. MapleMoose talked about having issues with TA22012.

Just after I said I would let people answer for themselves! I have no discipline. Smiling. Broadly.

[Imaaan in reply to Litatamon]

Must have mixed them up because I remembered someone having difficulty with that batch number.

And why smile when you can grin like a cheshire cat a la Alice n Wonderland

[Brightness14 in reply to pennyannie]

My new batch is TA22012 which is working as usual. Thyroid s of course

[pennyannie in reply to Brightness14]

Thank you :

[Litatamon in reply to Brightness14]

Thank you Brightness. Again, all the best & happy to hear about the positive changes for you.

[Imaaan in reply to Brightness14]

Glad to hear that the new batch is working for you. I'm curious to know as well so pls do share the batch number.