what do you think of these test result... - Thyroid UK

Thyroid UK

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what do you think of these test results ?

houselover profile image
15 Replies

hi all , would love your thoughts on these results ...

info first - 47 year old male , weight 110kg

taking 150mcg levo and 25mcg of T3 daily

also taking 160mg of propranolol daily for blood pressure (along with losartan)

test taken following normal protocol

would you change anything ?!

thanks in advance

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15 Replies
JAmanda profile image
JAmanda

If I still had symptoms I’d increase Levo to help bring both t4 and T3 up a little. Maybe just an extra 100 over the week. I’m always trialling to find the sweet spot!

NWA6 profile image
NWA6

How do you feel? I’m surprised that your TSh is so high, given the Levo and T3 you’re on, although to put it in context, you’re 110kg and I’m 69kg and I’m on pretty much the same amount of Levo/Lio. My FT4/3 results are similar to yours but my TSH is 0.03

SlowDragon profile image
SlowDragonAdministrator in reply to NWA6

He’s on high dose propranolol

SlowDragon profile image
SlowDragonAdministrator

How do you feel

That’s a high dose propranolol

When did you start taking propranolol…….before starting on levothyroxine or after?

Propranolol slows uptake and conversion of levothyroxine ….so much so it’s used to treat hyperthyroid patients

rejuvagencenter.com/hypothy...

Propranolol must only be reduced INCREDIBLY SLOWLY

Propranolol reduces magnesium levels too

ESSENTIAL to regularly retest vitamin D, folate, ferritin and B12

What vitamin supplements are you currently taking

Low vitamin D and low magnesium often go together

I was stuck on propranolol almost 20 years….you might find my profile info helpful. Took me 7-8 months to ween off 40mg propranolol

SlowDragon profile image
SlowDragonAdministrator

What was reason for your hypothyroidism

Autoimmune thyroid disease also called Hashimoto’s

RAi or thyroidectomy

houselover profile image
houselover

thanks for your input everyone , will try to give you a bit of history !

i started on propranolol about 7 years ago for high bp and stress and im aware of its effect on on the thyroid now ... seemed ok for a few years though , but i started piling weight on ( used to be about 90 kgs ) and my tsh went to just under the threshold but the doc wouldnt do anything and didnt tell me about the propranolol link ...thats when i started self medicating

the levo made me feel better but hasnt helped me lose weight so i started adding t3 about a month ago but it hasnt helped yet ...

im in the process of tapering off propranolol and swapping it with atenolol which is meant to be the least thyroid affecting and then im going to get off that as well !

supplements i take daily are a multivit with iron and milk thistle , but thats all for now

overall i dont feel that bad , but ive had problems with stomach ulcers and episodes of flushing that are pretty severe , and as mentioned the weight gain !

thanks all for your input

SlowDragon profile image
SlowDragonAdministrator in reply to houselover

Stomach ulcers …H pylori…. linked to autoimmune thyroid disease

thyroidpharmacist.com/artic...

endocrine-abstracts.org/ea/...

Suggest you get FULL thyroid and vitamin testing, including thyroid antibodies

You’re likely better to supplement separate vitamin supplements…..rather than just multivitamins

Propranolol affects PTH

labtestsonline.org.uk/tests...

Drugs that may decrease PTH include cimetidine and propranolol.

So can end up with low vitamin D and low magnesium

Bloods should be retested 6-8 weeks after each dose change or brand change in levothyroxine…..or after reduction in propranolol

For full Thyroid evaluation you need TSH, FT4 and FT3 plus both TPO and TG thyroid antibodies tested.

Very important to test vitamin D, folate, ferritin and B12

Low vitamin levels are extremely common, especially with autoimmune thyroid disease (Hashimoto’s or Ord’s thyroiditis)

Low vitamin levels common as we get older too

Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and before eating or drinking anything other than water and last dose levothyroxine 24 hours before test

On day before blood test, split T3 into 3 smaller doses, at roughly equal 8 hour intervals, taking last 1/3rd of daily dose approx 8-12 hours before test

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)

Private tests are available as NHS currently rarely tests Ft3 or all relevant vitamins

List of private testing options

thyroiduk.org/getting-a-dia...

Medichecks Thyroid plus antibodies and vitamins

medichecks.com/products/adv...

Blue Horizon Thyroid Premium Gold includes antibodies, cortisol and vitamins by DIY fingerprick test

bluehorizonbloodtests.co.uk...

If you can get GP to test vitamins and antibodies then cheapest option for just TSH, FT4 and FT3

£29 (via NHS private service ) and 10% off down to £26.10 if go on thyroid uk for code

thyroiduk.org/getting-a-dia...

monitormyhealth.org.uk/

NHS easy postal kit vitamin D test £29 via

vitamindtest.org.uk

If TPO or TG thyroid antibodies are high this is usually due to Hashimoto’s (commonly known in UK as autoimmune thyroid disease). Ord’s is autoimmune without goitre.

About 90% of all primary hypothyroidism in Uk is due to Hashimoto’s. Low vitamin levels are particularly common with Hashimoto’s. Gluten intolerance is often a hidden issue too

Link about thyroid blood tests

thyroiduk.org/getting-a-dia...

Link about Hashimoto’s

thyroiduk.org/hypothyroid-b...

List of hypothyroid symptoms

thyroiduk.org/if-you-are-un...

NWA6 profile image
NWA6 in reply to houselover

Good that you’re going to move away from the propranolol and just get your Vits/minerals tested and stop taking a multivitamin amd move over to tailored tablets.

SlowDragon profile image
SlowDragonAdministrator

Remember to click blue “reply” button otherwise other poster doesn’t get alert

houselover profile image
houselover

thank you - have tested negative for h-pylori multiple times and done the treatment course anyway just to be sure !

SlowDragon profile image
SlowDragonAdministrator in reply to houselover

Have you had BOTH TPO and TG thyroid antibodies tested

houselover profile image
houselover in reply to SlowDragon

im not sure , just tested what is in the results i posted ?

SlowDragon profile image
SlowDragonAdministrator in reply to houselover

Sorry…yes both tested in image in opening post

Both negative now

Ever tested antibodies by GP at diagnosis?

Not had thyroidectomy or RAI for Graves’ disease

Ever had ultrasound scan of thyroid?

About 90% of primary hypothyroidism is autoimmune thyroid disease also called Hashimoto’s, usually diagnosed by high thyroid antibodies

20% of Hashimoto's patients never have raised antibodies

healthunlocked.com/thyroidu...

Paul Robson on atrophied thyroid - especially if no TPO antibodies

paulrobinsonthyroid.com/cou...

Come back with new post once you get vitamin results

Stop multivitamins a week before test

Ideally only supplement what you need as good quality individual vitamins

How much have you managed to lower propranolol now

houselover profile image
houselover in reply to SlowDragon

hi , i can answer no to those questions , GP doesnt believe anything wrong so no testing done ...

as for propranolol im down to 20 x 2 a day , no problems to report and im hoping to stop completely by the end of next week .

i was wondering how long i should wait to get my thyroid tested again after stopping - does it need time for the propranolol to get out of my system and for the thyroid to start working normally again ?

thanks again

SlowDragon profile image
SlowDragonAdministrator in reply to houselover

That’s cutting propranolol very quickly

You might need to go slower

Reducing by 5mcg….wait 4-6 weeks…..reduce again by another 5mg etc

Last 5mg ….cut one day week….next week cut twice week….etc until stopped completely

Yes will need 6-8 weeks after stopping propranolol before testing

Always test as early as possible in morning before eating or drinking anything other than water and last dose levothyroxine 24 hours before test

Splitting T3 into 3 smaller doses spread through day at approx 8 hours intervals….last dose T3 8-12 hours before test

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