This is my previous post with my rather difficult experience with Metavive I and II
And This what i found about Nucleotides from a London Osteopath and Naturopath specialised in Nutrition.
" NOTE: There are a couple of contraindications for taking nucleotides as supplements. Because of its purine content, those of us who are genetically predisposed, have a history of, or suffer from gout are generally advised not to supplement nucleotides. Furthermore, the strong immune-enhancing effect prohibits the use of nucleotides for sufferers of auto-immune diseases and users of immune-repressive medications."
So this just confirm what i thought and Metavive is sold to us mainly Hashimoto sufferers with no warnings.
One advice if you want to take Metavive take the bovine one it contains more gland Metavive IV contains 65mg gland and only 15 mg nucleotides and Metavive III has 32mg gland and 8mg Nucleotides.
After months of trying with porcine Metavive and feeling more ill every day this makes me feel rather angry how can a company think it is OK to add Nucleotides to a supplement many autoimmune system sufferers will be taking and this without proper warnings shouldn't they create an alternative with or without Nucleotides Added this explains as well why some people on the forum found they were feeling well with the old formulation but started to get unwell with the new formulation when the nucleotides were added.