Disturb sleep

[sylus_911]

I am constantly waking up through the night and I'm a wake at 5 or 6 am and cant go back to sleep.I take my last dose of NDT at 4.15 pm.Can anyway help as to the reason why.?

[SlowDragon Administrator]

You need to retest TSH, Ft4 and Ft3 plus vitamin D, folate, ferritin and B12

Previous post shows low vitamin D and very low B12

Presumably you are working on improving these

Thyroid testing should be done as early as possible in morning before eating or drinking anything other than water and last 1/3rd of daily dose 8-12 hours before test

What vitamin supplements are you currently taking

[sylus_911 in reply to SlowDragon]

Hi slowdragon, my last blood test was in November. Tsh.0.21(0.34-5.6)T3.3.9(4.0-6.6)T4.8.5(7.9-20.0)..I have started taking B12 which is now 202(120-625)originally it was 175.Ferritin has come down to 102(11-307)it was 137.Folate is 9.6ug/1.

Vitamin D I was taking 800iu and am now

Taking 150iu,I ask the doctor to include a vit D test but he did,nt so until I get another test I dont know.

[SlowDragon Administrator in reply to sylus_911]

Tsh.0.21(0.34-5.6)

T3.3.9(4.0-6.6)

T4.8.5(7.9-20.0)

B12 which is now 202(120-625)

Ferritin has come down to 102(11-307)it was 137.

Folate is 9.6ug/1.

Vitamin D I was taking 800iu and am now

Was this test done as early as possible in morning before eating or drinking anything other than water and last 1/3 of NDT daily dose taken at roughly 8-12 hours before test

B12 is extremely low

Folate need range

Need to test vitamin D

£29 (via NHS private service ) and 10% off down to £26.10 if go on thyroid uk for code

thyroiduk.org/getting-a-dia...

monitormyhealth.org.uk/

Also vitamin D available as separate test via MMH

Or alternative Vitamin D NHS postal kit

vitamindtest.org.uk

[SlowDragon Administrator in reply to sylus_911]

Low B12

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid) may be beneficial.This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid

chriskresser.com/folate-vs-...

Many Hashimoto’s patients have MTHFR gene variation and can have trouble processing folic acid.

thyroidpharmacist.com/artic...

B vitamins best taken after breakfast

Igennus Super B is good quality and cheap vitamin B complex. Contains folate. Full dose is two tablets per day. Many/most people may only need one tablet per day. Certainly only start on one per day (or even half tablet per day for first couple of weeks)

Or Thorne Basic B is another option that contain folate, but is large capsule

If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

Low B12 symptoms

b12deficiency.info/signs-an...

With such low B12 result taking a B12 supplement as well as a B Complex (to balance all the B vitamins) initially for first 2-4 months, then once your serum B12 is over 500 (or Active B12 level has reached 70), stop the B12 and just carry on with the B Complex.

B12 sublingual lozenges

cytoplan.co.uk/shop-by-prod...

amazon.co.uk/Jarrow-Methylc...

healthline.com/nutrition/me...

[sylus_911 in reply to SlowDragon]

Hi slowdragon thank you for the information. I did have an active B12 test done back in June which was 92.000pmol/L (37.5)

[jrbarnes]

It's hard to say without seeing your thyroid levels so I can only relate my personal experience. I sleep poorly when my T3 levels are low. Have you tried to take a little of that NDT at 5am when you wake? It's possible the T3 might help you fall back asleep. You can also try a little around 11pm or midnight, depending on when you go to bed.

[Buddy195 Administrator]

Magnesium has helped me sleep better, in addition to thyroid medication and key vitamins being optimal. I take magnesium glycinate as it’s easier in the stomach.

[sylus_911 in reply to Buddy195]

Buddy195,I will give that a try.Thank you for your reply.

[SlowDragon Administrator in reply to sylus_911]

If you did testing as advised ....Ft3 is very low...suggests under medicated.....but if left longer than 12 hours it’s a false low

Many many members find small dose of T3 at bedtime improves sleep

[aspenca]

How is your cortisol levels? How is your cortisol/melatonin cycle? If your cortisol is low early A.M. your body will pull it's second hormone adrenaline and this will wake you up at night..I was doing the exact same thing you describe because my cortisol was low..

[Alanna012]

I read here that low T3 at night causes you to wake up. Try taking the dose of ndt a bit later in the evening or taking an extra tiny dose a couple of hours before sleep.

[Hashihouseman]

Too much t3 at the wrong time! You may be suppressing tsh at the beginning of the period when it’s naturally rising to healthy nighttime levels. Try spliting the dose if you don’t already and taking a small one on sleeping (it won’t kick in immediately) and then the larger one on waking. After a while your body may adapt, I found sleep is better if a little t3 is taken and takes effect from midnight onwards, tsh is naturally more active at night and it does other things than just stimulating the thyroid and nighttime maybe the time it’s needed for those other things e.g. skeletal bone formation/turnover. If tsh is too low and t3 too high at bedtime sleeping may be disturbed because their circadian rythym has been distorted.

[sylus_911 in reply to Hashihouseman]

Hi hashihousemanI take a grain and a quarter (75) when I get up and at 4.15 PM I take a small dose of 11.1/2. In all 86 1/2.I always thought if you take it to late that would keep you awake,well that's another thing I,ve learnt.My t3 was a bit low last time I had a blood test so raised it slightly from 81 to what I'm on now.I,ll give that a try and hopefully get some sleep.Thank you so much for your help.

[Hashihouseman]

Whenever I try taking t3 late pm (to try and keep the doses apart) it plays havoc and yes it seems counter intuitive to take any t3 just before sleep time but if I don’t, I wake up repeatedly and only get to sleep soundly if I take my (bigger) morning dose which I usually take at 6am at 4am! It seems to be my body craving for t3..... so now I try to head that craving off at the pass with a little pre-sleeping dose I’m starting to be convinced the key to dosing replacement is to control tsh in a circadian rhythm which means taking increasing dose portions from midnight to 1or 2pm then nothing until bedtime again, this seems to keep tsh lower during the day and allows its natural circadian rise from 3pm on to a peak around 2am.

[sylus_911 in reply to Hashihouseman]

HashihousemanThank you for your help.

[KT77]

That sounds like your cortisol is peaking too early. Magnesium lowers cortisol so try taking it right before you go to bed. For me its like a sleeping pill.