NDT V GLANDULARS.`

[sandysnow]

My private doctor, because of a significant rise in T3 and RT3, wants to switch from NDT (2 grains) over to glandulars. I have been trying to adhere to a Keto eating way, so that could have moved things around. I am concerned about this, as when Dr P reduced my Levo from 75 to 50 in readiness for going to NDT, I kept falling asleep. My weight is ok, I still have some slip ups with food and get the odd flare. What to do? I am also running out of my Thyroid S, which there seems to be a problem with. Any advice appreciated.

[Anthea55]

Does your doctor suggest any particular glandular? Dr P put me onto Metavive but they have reformulated it recently and some of us are finding problems with the new version.

I suggest that you search on here for it (on my screen it's the box top right marked 'Search HealthUnlocked'.

[shaws Administrator]

If you are wary of changing your dose, this is an excerpt from one of TUK's Advisers, who was also a scientist/researcher and expert in the use of T3.

" Old studies show that on average, most people convert more than 50% of their T4 to reverse T3; correspondingly, they convert less than 50% of T4 to the metabolically active hormone T3. And the levels of reverse T3 fluctuate up and down through the day.

Because of this, Im never confident of coming to a conclusion that someone has a problem with high reverse T3, not unless the person has had multiple measures of the reverse T3 over a 24-hour period. Like the TSH, free T4, free T3, reverse T3 levels vary dramatically every 30 minutes or so. Depending on when a persons blood is drawn or saliva taken. Sometimes the levels will vary enough so that a clinician will give the patient a different diagnosis from the one that he or she would have given 30-minutes before or after the blood or saliva sample was taken.

So blood levels vary rapidly. Because of this, I dont believe the reverse T3 or the other lab tests in general are very useful. However, I do believe the reverse T3 is useful under one circumstance: when we have enough measures to get averages over time,and when the levels are regularly way out of range. So, in my view, the reverse T3 can be useful, but I think its usefulness is limited, which is true of the TSH and other thyroid hormone levels.

tpauk.com/main/article/dr-j...