I'm moving from a combination of T4 and T3 to (hopefully) T3 only. T3 is definitely working for me a lot better than T4 mentally and physically.
My last T4 result was 10 (range 9-21) and so my endo doesn't want me to change much more T4 into T3 because then my T4 may/will drop below the reference range. However I would be happy to go below the reference range because levothyroxine does help me a little but not a lot. I also wonder if it may be creating too much reverse T3.
But T4 is converted into T3 inside some organs so maybe I would be better off taking some T4 and not going T3 only? Or can the cells in these organs use the synthetic T3 in the T3 pills?
I'd just like to try T3 only. It may not be best for me but I'll never know unless I try it and so far taking an equivalent amount of T3 to T4 has been far superior for me each time I've increased the T3 and lowered the T4. I still have some symptoms, they could be connected to my sleep and anxiety problems but they could be helped by going T3 only.