Low B.12 Injections?: My fiancé has been feeling... - Thyroid UK

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Low B.12 Injections?

Margo profile image
22 Replies

My fiancé has been feeling unwell and just had this blood results back, I wonder if anybody has opinion:-

TSH 3.18 0.3 - 5.0)

FT4 10.5 pool/L (7.9 - 26.0)

I am concerned about his B12 277 ng/L (120.0 - 900.0)

Serum folate 7.2 ug/L (2,5 - 9999.0)

As I recall in Japan anybody under 500 B12 is treated, is it possible he could insist on B12 injections?

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Margo profile image
Margo
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greygoose profile image
greygoose

In the UK? Very much doubt it. But, he does need to supplement.

Are those his first ever thyroid tests? They are saying he is technically hypo. You're hypo when your TSH gets to 3 - although you'd never get a UK doctor to admit that. What's more, his TSH is low compared to his FT4, which is only 14.36% through the range. One would expect a higher TSH with that result. His folate is rather low, too. I think he needs full thyroid testing.

Margo profile image
Margo in reply to greygoose

I agree with you @Greygoose, but I doubt if he will ever get a full thyroid panel.

I was wondering if he took the Jarrows B12 supplements and added some folate if that would help?

No it isn't his first thyroid blood test, he has been showing low for sometime. I have got him on Metavive x 1 and a thyroid support supplement, which he stopped before the blood test.

greygoose profile image
greygoose in reply to Margo

Those words strike terror through my veins: Thyroid Support! What sort of thyroid support? What are the ingredients? They usually contain iodine, which will probably make him worse, not better.

So, those results are on Metavive? Well, that's never going to get him a diagnosis. I doubt your GP ever will give him full testing, but couldn't he get a private blood test?

For the B12, I would suggest 5000 mcg sublingual methylcobalamin daily (Jarrows, yes) plus a daily B complex, such as Igennus. Just taking folate is not enough, he needs the whole range of B vits, because they all work together.

Margo profile image
Margo in reply to greygoose

Oh dear I think I have blown it again greygoose , yes containing iodine. Higher Nature Thyroid Support Formula, bought 4 pots because they were on offer....Yes the results are on Metavive I x 1 daily although he stopped 24 hours before the blood test. I am taking Thorne Basic B complex which contains folate, would they be as good as Igennus?

Yes I think a private test may be the way forward. Thank you

greygoose profile image
greygoose in reply to Margo

Is this the one?

12.5mg Vitamin C,

15mgNE Niacin,

3.3mg Vitamin B6,

60µg Folic acid,

5µg Vitamin B12,

1.25mg Iron,

25mg Magnesium,

2.5mg Zinc,

30µg Iodine,

1.25mg Manganese,

250µg Copper,

30µg Selenium,

450mg Tyrosine

I don't know how they've got the nerve to call it 'thyroid support'! It's just a common or garden multi-vit. And, as with all multi-vits, it's pretty useless, not to say dangerous for hypos.

A tiddly little dose of vit C, that's won't do much good for anyone.

Folic acid, when methylfolate would be better.

It doesn't say what sort of B12, so it's probably the cheaper, less absorbable, cyanocobalamin - and so little of it it wouldn't help anyway.

And, then it's got iron, which is going to block all the vitamins, so not much point in them being there! Plus, you should get iron/ferritin tested before taking any.

A rediculous dose of magnesium - but which magnesium? Probably the cheapest, least absorbable magnesium oxide.

Zinc and copper should both be tested before supplementing to make sure you need it - but hypos are usually high in copper and low in zinc, so you don't want to add more copper, because apart from making you ill, it would lower the zinc even further.

Iodine? I thought we all knew that hypos should not be taking iodine, it can make the situation far worse. He will already be getting iodine from the Metavive, and from his diet, so could be in excess, and that's bad.

So, being on offer wouldn't make me buy this rubbish - you couldn't give it to me. I think it should be returned to the pharmacy to be disposed of humainly.

Stopping Metavive 24 hours before the blood draw will not affect what he's already absorbed in the time he's been taking it. It will have lowered his TSH and raised his Frees - FT4 only slightly, perhaps, but certainly his FT3. And that will make a diagnosis unlikely.

Thorne Basic B complex is good, yes. :)

Margo profile image
Margo in reply to greygoose

Oh dear I can't believe I have been so stupid having read so many comments by you and others about multi vitamins. What can I say? Will try harder next time. I am actually going to print these replies off and will refer to them as I go along noting all the things to take. Thank you again.

greygoose profile image
greygoose in reply to Margo

Brain fog?

I know it sounds tempting when you read 'Thyroid support' on a bottle of pills. But, as I always say, if it sounds too good to be true, then it usually is. You can't 'support' your thyroid. And, by the time you get results like those above, it would be too late, anyway. And, for 'support', read 'stimulate', because that's what they do. And stimulating a sick gland is never a good idea.

Margo profile image
Margo in reply to greygoose

Yes greygoose it all makes sense, thank you.

greygoose profile image
greygoose in reply to Margo

You're welcome. :)

JAMV profile image
JAMV in reply to greygoose

My TSH is 2.1. Does that mean Im hypo? Doc says its normal.

greygoose profile image
greygoose in reply to JAMV

Well, it's not hypo - you're hypo when it gets to 3. But, it's not 'normal', either. A euthyroid TSH would never be over 2. What it means is that your thyroid is beginning to struggle.

When a doctor says 'normal', all he means is 'in-range'. He doesn't care where within the range, and doesn't understand about optimal positions within that range. It's all or nothing with a doctor. And, just testing TSH is totally inadequate. It doesn't tell them everything, as they like to think! You also need the FT4, FT3 and antibodies tested.

JAMV profile image
JAMV in reply to greygoose

My FT3 is 6.57 (4-8.3) FT4 is 1.52 (0.69-1.55)

greygoose profile image
greygoose in reply to JAMV

I really think it would be better if you started a new post, giving all the details - such as whether you are on thyroid hormone replacement or not - so that more people can see and advise, rather than tagging on to this very old post belonging to someone else. :)

SlowDragon profile image
SlowDragonAdministrator

Recommend you get vitamin D tested too plus ferritin and iron

Work on getting all four vitamins optimal

B12 too low and needs supplementing with daily vitamin B complex.

Exactly what “thyroid support” - most contain iodine which can make things a lot worse

And stop Metavive.....as greygoose says he will never get diagnosed as hypothyroid if on Metavive

Getting FULL thyroid and vitamin testing privately after. 6-8 weeks off of everything apart from vitamins

What’s his diet like? Vegan or vegetarian?

Supplementing a good quality daily vitamin B complex, one with folate in not folic acid may be beneficial.

chriskresser.com/folate-vs-...

B vitamins best taken in the morning after breakfast

Igennus Super B complex are nice small tablets. Often only need one tablet per day, not two. Certainly only start with one tablet per day after breakfast. Retesting levels in 6-8 weeks

Or Thorne Basic B or jarrow B-right are other options that contain folate, but both are large capsules

If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before any blood tests, as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

If he has Low B12 symptoms he likely needs separate B12 as well as B complex, at least for few weeks or months

b12deficiency.info/signs-an...

Margo profile image
Margo in reply to SlowDragon

Thank you SlowDragon , The D wasn't tested but Serum Ferritin:- 139 ng/mL (15.0 - 300)

Higher Nature Thyroid Support Formula with iodine. I now know wasn't a good idea, and he won't take them now.

Thank you have noted 6 - 8 weeks and will go for a private test. Can you please remind me of some of the names that do private testing as I have never gone down that route before.

I don't know if this has any relevance at all, but John has an 'Above high reference limit' Derived Fibrinogen level 5.75g/L (2.0 - 5.3) (never ever heard of Fibrinogen)

SlowDragon profile image
SlowDragonAdministrator in reply to Margo

Never heard of fibrinogen...but here’s info on it

labtestsonline.org/tests/fi...

SlowDragon profile image
SlowDragonAdministrator in reply to Margo

For full Thyroid evaluation you need TSH, FT4 and FT3 plus both TPO and TG thyroid antibodies tested. Also EXTREMELY important to test vitamin D, folate, ferritin and B12

Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and before eating or drinking anything other than water .

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip, best not mentioned to GP or phlebotomist)

Private tests are available as NHS currently rarely tests Ft3 or thyroid antibodies or all relevant vitamins

List of private testing options

thyroiduk.org.uk/tuk/testin...

Medichecks Thyroid plus ultra vitamin

medichecks.com/products/thy...

Medichecks often have special offers, if order on Thursdays

Thriva Thyroid plus vitamins

thriva.co/tests/thyroid-test

Blue Horizon Thyroid Premium Gold includes vitamins

bluehorizonbloodtests.co.uk...

If TPO or TG thyroid antibodies are high this is usually due to Hashimoto’s (commonly known in UK as autoimmune thyroid disease).

About 90% of all primary hypothyroidism in Uk is due to Hashimoto’s. Low vitamin levels are particularly common with Hashimoto’s. Gluten intolerance is often a hidden issue to.

Link about thyroid blood tests

thyroiduk.org/tuk/testing/t...

Link about antibodies and Hashimoto's

thyroiduk.org.uk/tuk/about_...

thyroiduk.org.uk/tuk/about_...

List of hypothyroid symptoms

thyroiduk.org.uk/tuk/about_...

Margo profile image
Margo in reply to SlowDragon

Thank you again SlowDragon

Other suggestions re low folates and B12 are found in non alcoholic fatty liver disease. Alcohol may affect levels of vitamins B12 and B9. If the ferritin levels are low this might be a sign of celiac disease which often goes with thyroid problems. Other causes may be pernicious anaemia with low B12 and B9.

Article might be of interest.

Low folate and B12 linked to severity of fatty liver disease

nutraingredients.com/articl...

Links fail with server so search engine may help.

Margo profile image
Margo

Thank you I will take a read Hidden . John was an alcoholic for 4 years, and I often wonder if he damaged himself at that time.

in reply to Margo

Who knows? A friend drank whisky neat more than a bottle a week but ate snacks and food . His liver was fine. It is just the very low folates with the B12 which might indicate a problem. Cutting present alcahols levels down using white wine cutting out spirits and supplementing B12 and B9 may help. Methylfolate was recommended by a thyroid contributor rather than B9 as being better absorbed than folic acid. You have to eat loads of of dark leaved vegetables but lambs liver is high in folates and B12. Myfooddata.com website using nutrient ranking tool to find foods over the recommended daily values of nutrients is great. I used global healing drops for B12 under the tongue and my vitamin levels were good after a year of taking it. You have to take B12 as well as B9 according to a member of T.U. NHS and online now has tests for vitamin d and thyroid lab tests at 25 pounds. Worth looking under food intolerance and vitamin tests NHS online.

Margo profile image
Margo

Thank you Hidden for your help. I think John drank a lot more than a bottle of whisky a week, I think it was a large bottle of Jack Daniels, starting with breakfast and anything else he could get hold of for four years. But that was 20 years ago. During this lock down we have both had a glass of red wine in the evening every night, when we only normally drink wine or anything else at weekends. We just find that one glass takes the edge off the worries and fears of the day. His diet is very good we eat a lot of fresh vegetables, but thank you for reminding me about the lambs liver, and the B12 drops.

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