Hashi's or not.

[lucylocks]

Hi

Can anyone please confirm if I have hashi's or not.

I was diagnosed hypo. eight years ago. Doctor said I did not have the autoimmune kind of hypothyroidism and prescribed levo. think he said antibodies were 58.

I have had several test with Medichecks over the years. Last year my

Thyroglobulin Antibodies were 115

I am sure the Doctors note at the time said I did not have autoimmunity and I seem to think that the result was written as 115 range 0 - 115 so thought I was borderline.

On looking back at my results it now written as 115 < 115 and a red dot on graph saying outside of normal range.

Thyroid Peroxidase Antibodies at the highest have bee 32.4 top of range 34.

The reason I want to make sure if I do in fact have hashi's is that I have just come back from holiday and have broke out with hives. I first thought it was prickly heat on my arms but it is now on my stomach which was covered with a top in the sun. (I was not sun bathing just sat and walking about in sun here in U.K.)

I did see an Immunologist 18 months ago because I started with cold urticaria (hives from the cold weather) he did lots of tests but nothing showed up. I mentioned thyroid antibodies and hashi's but he said for someone to have hashi's there AB's would have be in the thousands.

So do I actually have hashi's and if so could the hives be because of this.

Anyone else suffering with hives?

Any advice would be gratefully received.

Thank you.

[Paolatello]

My understanding is that if you have out of range antibodies you have autoimmune thyroid disease but someone might be able to elaborate further.

[lucylocks in reply to Paolatello]

Thank you.

[greygoose]

Just being hypo can make you susceptible to hives. You don't have to have Hashi's.

The best we can say about your labs is that Hashi's is unproven. A TgAB level of just over-range can be caused by all sorts of other things than Hashi's. It would have to be very high - perhaps not in the thousands, but a lot higher than that - to prove Hashi's.

On the other hand, you cannot prove that you don't have Hashi's with a blood test, because antibodies fluctuate. And, some people have Hashi's without ever having high antibodies. They are diagnosed by ultrasound.

[lucylocks in reply to greygoose]

Thank you.

[greygoose in reply to lucylocks]

You're welcome.

[SeasideSusie Remembering]

With Tg antibodies right at the very top limit of the range, and TPO antibodies virtually at the top, I would say that Hashi's is a certainty. Antibodies fluctuate and I'm sure the TPO would be over range at another time, just as much as both antibodies would show lower at some time. And apparently it is possible to have Hashi's but without raised antibodies.

I don't have Hashi's and I've never had hives so can't comment from personal experience, but if you Google "Hashi's and hives" it seems as though for some people there appears to be a connection.

[lucylocks in reply to SeasideSusie]

Thank you.

I thought it strange that the Immunologist said that the AB's have to be in the thousands to have hashi's. if that was the case why give a range for it.

I will try gluten free to see if it helps.

[bubbatetley in reply to SeasideSusie]

Happy new year , lets hope its a good one.. Thank you for all the advice you have given me over the years,, I have learnt so much.. 🎈🎉🎊🎀

[Treepie]

Not sure it matters ,the treatment is the same and if you have hives it needs treating .Many who have hashi find being gluten free helps.

[lucylocks in reply to Treepie]

Thank you.

Really wanted to confirm hashi's as I had read hives can be associated with it, but as greygoose says you can get then with non autoimmune hypothyroidism (which I was not aware of) Also I thought if it is hashi's going gluten free may help.

[HLAB35]

You could try taking histamine blockers like curcumin, nettle or quercetin on a regular basis to prevent outbreaks. Histamine has a complex relationship with our adrenals and thyroid. An intolerance to histamine can be because you don't make enough DAO enzyme to break it down. Symptoms may start with heartburn, puffy face, swollen glands, itchy red patches on skin and hives etc. Even though you may take precautions with diet, a seemingly benign meal can set off symptoms.

Link 1 is about low histamine diet reducing outbreaks of hives.

ncbi.nlm.nih.gov/pmc/articl...

Link 2 makes the connection between excess histamine and underactive thyroid.

drbeckycampbell.com/the-thy...

[lucylocks in reply to HLAB35]

Thank you for your reply and links.

I did find the reading very interesting.

I did eat a more variety of food whilst on holiday which could have set the hives off, but it has now been a week and they are still as bad.

Do you have any experience of the histamine blockers or DAO.

Any other info. would appreciated.

Many thanks.

[HLAB35 in reply to lucylocks]

Yes I do have experience of this through my daughter who takes Quercetin (Solgar brand I think) twice a day and drinks Nettle tea and she always has some antihistamines on hand. She has to watch her diet, but even then, something can surprise her, but she's had a much easier summer this year. I agree with Hypothyro that Piriton is better than Piriteze... I use it after seeing the dentist as something sets me off (he doesn't use latex gloves). The DAO enzyme supplements look expensive, but may be worth it to keep the worst symptoms at bay.

[lucylocks in reply to HLAB35]

Thank you, I will get some Quercetin and Nettle tea.

I have been taking fexofenadine but it is not really helping.

I will try Piriton to if it is any better.

Good to hear your daughter has had a better summer.

[Hypothyro]

Hi Lucylocks, as the others have said, can’t be sure it’s Hashi’s. Take an anti-histamine (Fexofenadine is good) & personally I would immediately take a Piriton tablet (not Piriteeze, as its a cheaper version of Piriton, that’s not as effective.). Good Luck 👍

[lucylocks in reply to Hypothyro]

Thank you.

I have been taking fexofenadine but it has not really helped.

It is strange as it does not itch like my cold hives, just gets hot.

I will try the Piriton.

Also going to try gluten free to see if that helps.

[Assiya]

How you doing Lucylocks ?

[lucylocks in reply to Assiya]

Hi

The hives finally settle after a bout three weeks, I think it was a reaction to the sun.