ndt difference peak and trough: on ndt how much... - Thyroid UK

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ndt difference peak and trough

ramsfs10 profile image
15 Replies

on ndt how much difference in t3 blood test on peak and trough for a 24 hour period.. my t3 is just above range when tested at peak

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ramsfs10
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15 Replies
Jodypody profile image
Jodypody

Do you take your NDT on the day of your test?

ramsfs10 profile image
ramsfs10 in reply toJodypody

i have a great doc that prescribes based on symptoms but he want blood test done 4-5 hours after morning ndt taken. i take 1.5 grain 6am blood test at 10am and .5 grain 12pm.. my t3 came back 4.8 with range of 2.0-4.2.. i feel great was just curious how low you think my trough would be.. i read somewhere it was 20 percent lower with no ndt before test

ramsfs10 profile image
ramsfs10 in reply toramsfs10

although i do get fatigues around 7pm.. tried upping a 4th grain and had crazy heart palps

Jodypody profile image
Jodypody in reply toramsfs10

I never take before test. Try not doing next time. Which ones are you taking?

ramsfs10 profile image
ramsfs10 in reply toJodypody

naturethroid

greygoose profile image
greygoose

Your doctor doesn't know much about thyroid, does he. If you test 4-5 hours after taking your NDT, all you are testing is the dose you just took. You should leave a 12 hour gap, so that you catch the T3 half-way between doses - the trough.

How much difference there would be is not easy to say. Some people use 20% as a rough guide, but I don't know how accurate that is. And that doesn't take conversion of T4 into account. When doctors tell you to take your hormone before the test, I always suspect them of avoiding giving you a rise in dose! So, he may seem nice, but beware! He's either ignorant or sneaky. :)

ramsfs10 profile image
ramsfs10 in reply togreygoose

thanks for respnse. i will just have to get private test i guess.

ramsfs10 profile image
ramsfs10 in reply togreygoose

also i have tried to take bulk of meds on first dose and feel way over medicated and drained at night ao i feel i burn through t3 quickly. i like frequent dosing mich better

greygoose profile image
greygoose in reply toramsfs10

Frequent dosing is better for some people. But, not because you 'burn through' the T3. T3 stays in the blood for 24 hours. But, what gets into the cells stay there for about three days. :)

ramsfs10 profile image
ramsfs10 in reply togreygoose

i am confused tho about testing. shouldnt the peak and the trough of t3 be important because being overmedicated sucks really bad.

greygoose profile image
greygoose in reply toramsfs10

Testing should be 12 hours away from taking your dose. If you have the blood drawn just after taking your T3, it's very easy to think you're over-medicated when you aren't.

Yes, over-medication 'sucks really bad', but if it 'sucks' that much, you'll know from the symptoms, won't you. :)

ramsfs10 profile image
ramsfs10 in reply togreygoose

another question sorry. will i ever be back to 100 percent again on meds? cause i used to be able to work out as long and as much as i want.. im so much better but def not how i used to be before all this.

greygoose profile image
greygoose in reply toramsfs10

Impossible question to answer. It depends on so many things - not least the knowledge of your endo, so you're off to a bad start there!

And, it depends how long you've been hypo before diagnosis. The longer you go untreated, the more difficult it is to come back. More thyroid hormone receptors have been closed off, and you have to be taking enough hormone to reopen them.

And, it's not just about hormones, it's also about nutrition - all your nutrients need to be optimal for the thyroid hormone to work.

Some people do get back to very close to 100%, but not everybody.

ramsfs10 profile image
ramsfs10 in reply togreygoose

also i tested negative for hashis so no idea why my thyroid was in gutter.

greygoose profile image
greygoose in reply toramsfs10

It's very difficult to prove you don't have Hashi's. And, one negative test of one antibody won't cut it. Antibodies fluctuate all the time, so you have to catch them at the right time. Plus there are two antibodies for Hashi's - TPO and Tg antibodies. And, on top of that, not everybody with Hashi's develops high antibodies. And, if that weren't enough, a lot of doctors swear blind you don't have Hashi's, when the blood test results scream that you do!

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