80 mcg sounds like nothing at all. With a TSH like that you need the maximum increase of 25 mcg - and probably a couple more increases at six weekly intervals after that.
goose....i would be interested to know how you feel about taking thyroid medication at night as the OP indicated he does. i have heard this can be good for absorption as there is less chance of calcium interfering with uptake. my endo suggested this as I am also on steroids requiring food with dose. my pharmacist, however, strongly discouraged this as it will 'confuse the body, interrupt circadian rhythm, and fail to properly replicate a healthy physiological thyroid response'. stefcon....did you notice any difference when switching to nighttime dose?
I think, like everything else to do with thyroid, it suits some people but not others. There should be no hard and fast rules laid down about what you should and shouldn't do. People should be free to find out what suits them best. I certainly wouldn't take advice from a pharmacist! Not on any subject.
I've tried both, and personally, don't find any difference in the way I feel. At the moment, I take mine in the morning, because it fits in better with my eating patterns and the other things I need to take. But, either way is ok by me.
Other people find they feel much better in the morning, when they take it at night. I think a hypo's body is already pretty confused, so a little more won't make much difference. However, I do believe that the bulk of T3 is produced during the night, when all the reparation and regeneration is taking place. So, I would be inclined to disagree with the pharmacist.
I tried taking Levo at night because some people rave about it. I only took 25mcg at the time. I didn't sleep a wink for a full week. By which time I was on my knees and went back to morning dosing. Others love it. Just goes to show how different we are.
oh boy!!! very glad you said this. travelling for work right now. you could have saved me from a very miserable business trip if I had the same experience.
I agree about the reparation. Our bodies are smart; they accomplish a lot when we're sleeping. I do talk with my pharmacist about meds sometimes but more to find out how some meds are affecting patients in real time. But I don't ask them for medical advice. In fact more and more I trust myself and my own research more than some of my doctors. I think it's my gut feeling I trust and my Bull#@$& detector.🐱
Yep. I try to. When I don't, things don't go well. It's a good life rule too. Don't try to control the Universe. Just let it work for you. Sometimes very hard for me to get out of my own way.🐱
In my not inconsiderable experience, the 25 mcg increases are justified 99% of the time. But no-one should be dosing by the TSH. The important number is the FT3, the TSH, once it's down under one, is more or less irrelevant. You should dose to keep it in-range. Yes, if the TSH is suppressed, it will shut-down the thyroid, but so what? The thyroid is not capable of supplying enough hormone to keep you well, anyway. And, the great thing about thyroids is that, if you run out of levo or whatever, it will just bounce back and carry on where it left off. An awful lot of hypos need an amount of thyroid hormone that will suppress their TSH, and reducing the dose to keep the TSH in-range, will just lead to keeping the patient sick. Of course a blood test is just a snap-shoot, but it's the best guide we have, and should only be used in conjunction with how you feel, anyway. It's not set in stone.
However, I'm afraid antibodies will not give you any idea how fast the disease is progressing. They will just tell her if she has Hashi's. Not all cases of hypo are caused by Hashi's, so not everybody has antibodies - not even all Hashi's people have antibodies. The number of them certainly doesn't tell you anything about the state of the Hashi's, either, because antibodies fluctuate. They are highest just after an immune system attack on the thyroid, when they come in to clear up the 'mess'. They then reduce again. So, you cannot deduce anything much about your hypothyroidism from testing them.
It's necessary for the majority of people on here. They cannot be well with an in-range TSH. And, as for the HPT axis, that is already compromised when you start to take thyroid hormone replacement. I know about conversion, but that is only one thing that needs to be taken into consideration. So, what are the other endocrine processes the TSH is related to?
Besides, I wasn't telling the OP to suppress her TSH, I was just saying that raising the levo to 80 mcg is hardly likely to bring her TSH down into range, so I don't really know why we're discussion a suppressed TSH. But, as we're on the subject, what, according to you, are the long-term 'dangers' of a suppressed TSH?
let me get a direct response to you. i do not want to further confuse this thread. i missed the post regarding RAI and apologize for my misunderstanding. let me clean this up and maybe start something new to discuss suppression.
The OP hasn't got a thyroid anymore after RAI, so it can't be "shut down". Needs a full replacement dose to remove symptoms. 25mcg is the usual increase, esp since most people are aiming for a TSH or between 0.2 and 1.
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