Thyroid hormone replacement: an iatrogenic problem

[Andyb1205]

Anyone have access to the Wiley Online Library or the PDF of this article? Would love to get my hands on it!

Abstract:

“Thyroid hormone replacement is one of the very few medical treatments devised in the 19th century that still survive. It is safe, very effective and hailed as a major success by patients and clinicians. Currently, it is arguably the most contentious issue in clinical endocrinology. The current controversy and patient disquiet began in the early 1970s, when on theoretical grounds and without proper assessment, the serum thyrotropin (TSH) concentration was adopted as the means of assessing the adequacy of thyroxine replacement. The published literature shows that the serum TSH concentration is a poor indicator of clinical status in patients on thyroxine. The adequacy of thyroxine replacement should be assessed clinically with the serum T3 being measured, when required, to detect over‐replacement.”

onlinelibrary.wiley.com/doi...

[humanbean]

sci-hub.tw/10.1111/j.1742-1...

I would recommend downloading the paper and saving it. Sci-hub domains have a habit of disappearing because publishers take them to court.

[Andyb1205 in reply to humanbean]

Thank you very much and done! 🙂

[shaws Administrator]

I have posted earlier the following in a similar vein. We, the patients, find out there's something not quite right when we don't progress but doctors or endos might well prescribe for a symptom rather than a proper dose of hormones.

hormonerestoration.com/Docs...

[Beata_s]

academic.oup.com/labmed/art...