Confusing second set of tests

[Taurinegb]

Please help me understand my most recent tests compared to me first ones.

Old verses now results:

TSH was 0.402 mIU/L now 0.124

FT4 was 19.72 pmol/L now 12.3

FT3 was 3.82 pmol/L now is the same 3.82

T4 was 96.7 nmol/L now 62.5 nmol/L

Anti-thyroidperoxidase was 83.52 kIU/L now 103.0

Anti-Thyroglobulin was 34.37 now 26.6 kU/L

I'm confused because I've been taking T3 for about 2 months now and that hasn't changed but also that my T4 has gone down but so has my TSH?

[startagaingirl]

Hi - first off, you really need to give ranges as labs differ and it is extremely difficult to interpret results without them.

Second - to see if there is a true comparison possible - were both tests done at the same time of day, both with the same meals/timing of meals (if any) before? With the same number of hours after previous dose of thyroid meds?

One thing I can say, because your TpoAb has gone up, you have had an immune attack on your thyroid between the tests.

Gillian

[Taurinegb in reply to startagaingirl]

Is it safe to say my T3 levels haven't gone up though? I've been taking it for a while now so the Cytomel is a sugar pill?

[SeasideSusie Remembering in reply to Taurinegb]

Did you buy it from a member recommended reliable supplier - don't name the supplier on the forum but you can say if it came from, say, Greece and give the brand name - or did you buy it from a bodybuilding site?

When was your last dose of T3 before the blood test?

[greygoose in reply to Taurinegb]

No, of course it isn't a sugar pill. You have Hashi's - Hashimoto's Thyroiditis aka Autoimmune Thyroiditis - which means that your levels are going to go up and down all the time.

However, your pituitary has registered that you are getting some T3 into your system, which is one of the reasons it's gone down. And your FT4 has gone down because you're taking T3, so the body only holds on to as much as it needs, and it doesn't need as much.

But we can't come to any definite conclusions unless you answer startagaingirl's questions about test conditions. Because TSH and FT3 levels vary throughout the day. So, it's not safe to say anything.

[Taurinegb]

I have re-posted my results just incase this response is not seen.

The ranges are as follows:

TSH was 0.402 mIU/L now 0.124 Range 0.27 to 4.3

FT4 was 19.72 pmol/L now 12.3 Range 12 to 23

FT3 was 3.82 pmol/L now is the same 3.82 Range 3.1 to 6.8

T4 was 96.7 nmol/L now 62.5 nmol/L Range 64.5 to 142

Anti-thyroidperoxidase was 83.52 kIU/L now 103.0 Range 0 to 34

Anti-Thyroglobulin was 34.37 now 26.6 kU/L Range 0 to 115

I'm confused because I've been taking 12.5 mg of T3 (Brand name is Tiromel and I was referred that info) for about 2 ½ months now but my T3 hasn't gone up.

Also, I lowered my T4 intake from 125mg a day to 100mg a day because I was worried if I stayed at the 125mg and also took the 12.5mg of T3 it would be too much.

Also, why would one type of antibodies go up and the other antibodies go down?

Thank you for your help.

[SilverAvocado]

In my own experience of self medicating (on NDT, which contains T3 and T4), the freeT3 goes up and down quite erratically, even though I am constantly increasing the dose.

TSH and freeT4 always alter as you'd expect - TSH going down and freeT4 going up. Yours has done the same, with your TSH going down to reflect that you're taking more hormone ( I see that you've decreased T4 at the same time. T3 is about 3-6x as powerful as T4, so you've still had an overall increase).

Any explanation for why this is is kind of a guess. In my case, my freeT3 has been at the top of the range, and I've increased about 5 times and it hasn't raised at all. The best guess I've got is that I've been increasing the amount of activity I do, and so the T3 is getting used up. My symptoms have been reducing every time I increase, and I'm definitely able to do more each time. Symptoms are the most important thing, so if you're feeling better it doesn't matter what shows up on the blood test.

Your freeT3 is still very low, so you've got room for plenty of increases. This disappearing freeT3 is quite a good thing I think, as it means the blood tests indicate more and more increasing is possible.