Cynomel T3

[ChrisH100]

Hello

Could I ask if anyone on this forum has had good experiences with the above T3? Thanks Chris

[greygoose]

Oh, yes, absolutely. Any other questions?

[ChrisH100 in reply to greygoose]

Great - What dose do you take, do you split over the day and do you take it with t4 -

[greygoose in reply to ChrisH100]

Oh, I'm not still taking Cynomel. But, I've never taken it with T4, never split the dose, and have been on all sorts of doses from 25 - 225. I do best on 75 mcg.

[maxart]

Yes - absolutely. It's keeping me feeling something near normal!

[endomad]

i have been taking cynomel for last 16 months, i prefer it to the one i got from nhs its less aggressive i take 75mcg 3-4am and another 25mcg around 11am if its going to be a busy day.

[ChrisH100 in reply to endomad]

How do you feel - were you on t4 before....

[endomad in reply to ChrisH100]

T4 did not agree with me and i became very ill on it, i have not tried t3/t4 combo as i never want to feel as ill as i did on levo ever again.

I am 80% better i still get a lot of pain in my hips, knees, ankles and feet, the pain is mainly in the joint but also in the bone and muscle when bad. My sleep is not good at night and I still feel tired a lot but not the bone crunching fatigue i had before treatment where i could sleep 20 out 24 hours a day.

T3 is not a magic bullet like everyone thinks, i have been on it 16 months and still not back to normal activity. My SHBG is lower than 70 which means my cells are still not fully active with t3. A saliva test shows my cortisol is very low and i am estrogen dominant both work against t3.

So yes i am better but a long way from the competitive sportswoman i was before my TT. xx

[Clutter]

ChrisH100,

Are you asking about French Sanofi Aventis Cynomel or Mexican Grossman Cynomel?

Bear in mind that T3 is 3 x stronger than Levothyroxine and the dose you require will be individual to you. 6.25mcg - 12.5mcg added to Levothyroxine is often sufficient. If you are switching to T3 only say what dose Levothyroxine you are taking and members can estimate the equivalent dose.

[ChrisH100 in reply to Clutter]

Thanks Clutter - since taking t4 in Feb 17 I feel so much worse I have more symptoms now than I ever did. I'm currently on 150 mcg but still no change - I've just done medicheck for ft3 and rt3 as t4 isn't making any difference. I feel my condition is more cortisol related and that's why conversion is proving to be a problem - I want to try t3 to see if it makes any difference - not sure if I should take on it's own or add to t4? What would you suggest it's Mexican cynomel by the way....

[Clutter in reply to ChrisH100]

ChrisH100,

I would recommend adding some T3 to Levothyroxine initially. If you post your results and ranges we can advise whether or not you need to reduce Levothyroxine dose when you add T3. It's advisable to start by adding 6.25mcg T3 to see how well you tolerate T3.

[JudithW in reply to Clutter]

Hi Clutter 6.25 mcg is a very small amount, the body produces about 30mcg in a day. If conversion is a problem ie T4 is not converting to T3 due to a problem with Deodinase, or T4 is converting to rT3 in greater amounts than T3, ie the ratio is wrong, the only way to rectify either of them is to take T3. With the rT3 > than T3 then T4 has to be stopped, so that rT3 is got rid of from the body and of course the replacement T3 is needed.

[Clutter in reply to JudithW]

JudithW,

Yes, I know it's a small dose. Once a person knows that they are tolerating T3 they can increase dose as required.

[endomad in reply to ChrisH100]

is you suspect cortisol problems t3 will not make much difference as low cortisol blocks t3 absorption. I take a big dose of t3 but still have hypo symptoms as my low cortisol hinders it. T3 will help chase out RT3 if that is a prob, which it was for me. Depending how low your cortisol is and you need testing as it cant be guessed, some say CT3M will help but it didnt for me.

[ChrisH100 in reply to endomad]

When you said you felt very ill on t4 what symptoms did you have could I ask...

[endomad in reply to ChrisH100]

extreme pain all over, all joints, nerve damage on skin, frozen shoulder, shaking, sweating, heat flashes, unable to walk more than few mins, chronic diarrhea, stomach pain, eye pain and visual disturbances, unable to hold coherent conversation forgetting words, zoning out, lost of appetite but big weight gain thats just what i remember off the top of my head

[ChrisH100 in reply to endomad]

I have similar symptoms to you - And you started to feel better when you stopped taking t4 and took t3 instead? How soon did you feel a difference - do you have hashimotos ? sorry for all the questions? Im really struggling with if all Chris

[endomad in reply to ChrisH100]

No i dont have hashi's, it took few months to start feeling a bit better, i was pretty much in bed or on sofa. I gradually started moving about and doing a bit more. I have never had this wide awake, energetic feeling from t3 that people talk about. I am still stiff, achy and tired in the mornings, i find it hard to get going.

T3 has not restored the active life i had before, i have limited energy and i have to think what i allocate it to..getting up in morning, work, walk dog, if i have a night out i will be in bed for 2 days, if i over do exercise i will be in bed for 2 days, i literally have no additional energy, if i use more one day i have none left for few days and i can hardly walk. I use the spoons theory.

I only know one person personally who has got really well and back to full strength after thyroid crash. Everyone else is along the spectrum but not back to who they were, most of us seem to still have symptoms and set backs, so i have to accept my limitations now, which isnt easy.

I try not to think next year i will be back to daily horse riding, running half marathons each month, the banter and fun of running at night with army buddies, rock climbing and surfing weekends that was me before TT

I miss my fit strong body, i occasionally cry at the loss of the life i had before, i grieve for the life i had and how diminished my life is now in comparison. I am 100 times better than i was but still another 100 miles away from WHO i was. I was told i need to accept my new normal, i have great days and shit days, i am having to learn to accept it. For me there is no magic pill, supplement, tests, diet just being the best i can each day, constantly searching for THE THING that will give me my life 100% back has made me resentful, so now i find fun and happiness in what i can do xxxx

[ChrisH100]

Ok - thanks! should get my results back next week so will post for comment...do you take at the same time as t4?

[tzracer]

I haven't had any issues with the Grossman T3, taking a quarter with 150mcg of levothyroxin in the morning and another quarter 12hrs later.

Hope it works out ok for you

[JudithW]

Hi Chris how are you doing now. If your problem is the rT3/T3 ratio is wrong, and you have not done so already you need to stop taking the T4. T4 is converted to the rT3. I used to think rT3 blocked the receptors in the cells so T3 (which was diminished in amount any way) could not enter. I have recently read a paper which I need to re read to assimilate correctly that disabuses this theory.