Reposting - any comments on my results? Please.

[mb008]

Hi,

I'm reposting as I didn't have any replies I'm afraid.

I'm undermedicated I think , but want to use this as the baseline to switch to NDT.

Also, my B12 is very high. I thought our bodies just got rid of any excess. How does it builds up to these levels?

I have been healing my gut, so looks like it's working which is good - although how do you know if it has worked?

Thanks in advance..

M

[Nanaedake]

B12 could be high because you are healthy and eat a great diet! some countries seem to have higher ranges than us. Ranges are what most people fall into but I suppose there could be individual variation. If you want to check things out then read about kidneys as they clear B12 from your body and ask your GP to check it out for peace of mind.

[Clutter]

Mb008,

You are a little undermedicated to have TSH 2.03 and FT4 and FT3 are both less than halfway through range. If you switch to NDT FT4 will normally be lower than when you were taking Levothyroxine and most people will need FT3 >5.0 which is likely to suppress TSH <0.1.

Thyroid peroxidase antibodies are positive for autoimmune thyroid disease (Hashimoto's). There is no cure for Hashimoto's which causes 90% of hypothyroidism. Levothyroxine treatment is for the low thyroid levels it causes. Many people have found that 100% gluten-free diet is helpful in reducing Hashi flares, symptoms and eventually antibodies.

chriskresser.com/the-gluten...

thyroiduk.org.uk/tuk/about_...

B12 is high when you supplement but excess is excreted in urine so its not dangerous to have high B12. You could reduce dose if you wish.

Folate could be higher. You could supplement 400mcg folic acid for 3-4 months to raise folate.

Ferritin is optimal half way through range.

CRP is low which is good.

[helvella Administrator Thyroid UK]

Posts about B12 are on-topic here in Thyroid UK and perfectly reasonable. However, the Pernicious Anaemia Society forum is where there is much experience and knowledge about B12. You can find the forum by following this link:

healthunlocked.com/pasoc

High B12 when supplementing is one thing, but high without perhaps needs some explanation.

[SeasideSusie Remembering]

mb008 Yes, you are under medicated. The aim of a treated hypo patient generally is for TSH to be 1 or below or wherever it is needed for FT4 and FT3 to be in the upper part of their respective reference ranges.

If you had an increase in your Levo then your TSH would reduce and your free Ts would increase and remaining hypo symptoms should resolve.

You don't appear to have a conversion problem. Good conversion takes place when FT4: FT3 ratio is 4:1 or less, yours is 16.2 : 4.23 = 3.82 : 1

Why do you want to change to NDT? As you don't appear to have a conversion problem, I can't see a reason to start funding your own meds and possibly having to do all future blood tests privately. And as you're only on 25mcg Levo, according to your thread a couple of weeks ago, increasing Levo from a baby dose to a decent dose seems to be the sensible option.

**

As you have Hashi's, are you strictly gluten free and supplementing with selenium L-selenomethionine 200mcg daily to help reduce the antibodies?

**

How much B12 are you supplementing? You don't have to worry about your current level. The recommended level is very top of range, even 900-1000 for us hypos so you are at the right level. I keep mine at around 1000 now by supplementing 1000mcg sublingual methylcobalamin lozenges three times a week.

**

Your folate level is very low, it should be at least half way through it's range, so 27+ with that range, and when B12 is nice and high it doesn't matter if folate is high in It's range. When taking B12 we need a B Complex to balance all the B vitamins, so if you buy one that contains 400mcg methylfolate that will help raise your folate level - look at Thorne Basic B or Metabolics B Complex.

**

Ferritin and CRP are fine.

[mb008 in reply to SeasideSusie]

Thanks for replying. Reason for trying NDT is because I still have symptoms and in particular hair loss has increased a lot since being on Levo. I look as I've aged rapidly as well. I may increase Levo, as you say and see how I go. Thanks again -It's appreciated.

[mb008 in reply to SeasideSusie]

Hi, in answer to your b12 question I was supplementing 5,000iu daily. Will reduce to weekly now I think.