I posted a few questions the other day about my T3 addition but no one responded. So let me try this question. I am extremely sensitive to meds, especially new add ons. Dr prescribed at my request T3 Generic for Cytomel. She wanted 5mcg once daily and drop then my synthroid dose. Question is...... i started by a quarter pill in the morning for a few days and now i added a quarter in the afternoon. so far so good. I am going to wait a little to let my body adjust then I was wondering should i start doing a half morning and then add a half in the afternoon after a few days? (totaling 2.5 morning/2.5afternoon) or is it better doing a quarter pill 4 times a day to prevent palpitations and insomnia? I know you all are laughing right now , but i am serious about how sensitive I am. A few yrs ago before i knew about the hashi's and they just diagnosed me with the usual anxiety/depression because no one checked my thyroid panel or antibodies they put me on SSRis and benzos! Yuck! I started the smallest dose of celexa 10 mg and got so sick i had to break it in half!!!! Yes Hslf of the minimum dose. I want to prevent getting so super sick and/or the tremors/shakes that T3 can give you. I am just feeling this out yet. I really don't know if T3 added in with my synthroid is even the correct answer yet it is too soon. I do know i had terrible joint pain on T4 only that is gone now so far. Hair still falling out but I have more energy already, just no weight loss yet. Any advice welcomed please!