Spoiler alert: doctors are d***s.
Okay, aside from LOLing furiously re 'non-compliance' (hahahahahaHAHAHAHhahaha) being the leading cause of lingering uat I did wonder how people who regard themselves as scientists can follow a scientific protocol all the way through their case study until they find themselves perplexed by something... so they simply guess that the patient is lying - ?? Sure why not. Scientific supersleuthing!
(I was particularly aggrieved to read that because I'm nothing if not compliant in taking my meds every single day at the same time every day and I hate to think that my gp is secretly thinking I lie about it.)
Anyway, I was just musing on what might account for the success of the weekly protocol. Could it be that after a massive dose of levo the patient enjoys a nice substantial shot of hormone for a significant time instead of eking it out over the week? Could it be that higher blood levels of levo for part of the week is more therapeutic than lower doses all week long?
I don't know enough about the rise and fall of hormone in your blood to know how it works, but we do know that if you take your dose of levo right before a blood test it can come out high. What if you took your weekly dose and the t4 kept climbing (and converting to t3, which also kept climbing) until some time later in the week, when it began to fall, and the cumulative effect of those 'high' days was more effective than the day-to-day dose?
Anyone want to weigh in on this? helvella?