At last our latest paper is out in the European Thyroid Journal online:
Eur Thyroid J
DOI: 10.1159/000447967. This journal is very cagy about letting people have access to the whole text, but allow the summary. The essential findings are that in health, subjects defined by the FT3 normal range are not the same, independently of where they lie in the range. As you go up the range, you move from the good T4-T3 converters with low FT3 to the poor ones with high FT3. This has implications for later treatment and whether or not T3 will be needed when the thyroid fails. It suggests the need to monitor healthy people for their FT4, FT3 and TSH when well so as to discern the appropriate treatment should they fall ill later on. This would avoid the fruitless scratching about in ignorance by the GP/endocrinologist who otherwise wouldn't know your genetic makeup and its implications for how good or bad a converter you are, and therefore would have to start, as nowadays, without having appropriate information to treat with just T4 or with a combo of T4/T3. This paper continues the story of the variability and uniqueness of individuals in how their thyroid and body work together.